|Description||Acetylcholine is an organic molecule that acts as a neurotransmitter in many organisms, including humans.|
Fesoterodine Fumarate is an antimuscarinic agent and is rapidly de-esterified to its active metabolite 5-hydroxymethyl tolterodine that is a muscarinic receptor...
Atropine is is a naturally occurring tropane alkaloid extracted from deadly nightshade acts as a competitive muscarinic acetylcholine receptor antagonist.
Scopolamine is an anti-muscarinic and cholinolytic alkaloid that inhibits parasympathetic-cholinergic system. The central effects include hallucinations, disori...
Desfesoterodine is the active metabolite of fesoterodine as its isobutyrate ester.
Gallamine Triethiodide is a cholinergic receptor blocker with an IC50 of 68.0 ± 8.4 μM. It is is a non-depolarising muscle relaxant.
Espatropate is a Muscarinic receptor antagonist originated by Pfizer. It is a bronchodilator with antimuscarinic activity. No development was reported for the t...
This active molecular is a muscarinic agonist agent.
Diphenidol HCl is a potent antagonist of muscarinic M2 and M3 receptor with pKb of 6.72 and 7.02, respectively, used in the treatment of vomiting and vertigo.
Nuvenzepine, a new pirenzepine-analog, is an mAChR antagonist, administered intraduodenally, displayed a long-lasting and dose-dependent inhibition of neostigmi...
Oxybutynin is an anticholinergic medication used to relieve urinary and bladder difficulties.
Biperiden is an antiparkinsonian agent, which is the selective central M1 cholinoreceptors blocker. It is used for the adjunctive treatment of all forms of Park...
AC260584 is a potent and selective muscarinic M₁ receptor allosteric agonist (pEC50= 7.6). Studies indicated that AC260584 has a behavioral profile consistent w...
Darifenacin exerts non-parallel rightward displacement of the agonist curve and also significant depression of the maximum response (+)-cis-Dioxolane produced c...
Benzquinamide hydrochloride is an antiemetic compound with antihistaminic, anticholinergic and sedative properties. The mechanism of action is not quite sure an...
Muscarinic M3 receptor antagoinst. Used in treatment of urinary incontinence.
Imidafenacin(KRP-197; ONO-8025) is a potent and selective inhibitor of M3 receptors with Kb of 0.317 nM; less potent for M2 receptors(IC50=4.13 nM).
Propantheline Bromide is an antimuscarinic agent used as an antispasmodic for the treatment of ulcers.
Anisotropine methyl bromide
Anisotropine methylbromide is a muscarinic antagonist and antispasmodic. It was an adjunct in the treatment of peptic ulcer and promoted as being more specific ...
VU0152100 is a selective and positive allosteric modulators of M4 receptor. It has shown a potent positive allosteric modulators that increase the response of t...
Tarafenacin is a highly selective M3 muscarinic receptor antagonist. It was the most potent in inhibiting carbachol-induced bladder contractions of the anti-ch...