|Description||ACET, a potent and selective GluR5-containing kainate receptor antagonist, has been found to exhibit activities in blocking induction of NMDA receptor-independent long term potentiation (LTP) at some extent.|
|Purity||≥98% by HPLC|
VU 0155041 is a potent positive allosteric modulator at mGlu4 receptors (EC50 = 798 and 693 nM at human and rat mGlu4 receptors, respectively). VU 0155041 displ...
RG7090 is a negative modulator of metabotropic glutamate receptor subtype 5 (mGluR5; GRM5).
Ro 64-5229 is a selective, non-competitive mGlu2 antagonist.
CPPHA is a selective positive allosteric modulator of mGluR5 receptor. It is thought to act at a novel allosteric site and potentiates mGlu5 responses by a mech...
LY 456236 hydrochloride
LY 456236 hydrochloride is a mGlu1 receptor antagonist with IC50 value of 143 nM. It may be used in the treatment of chronic pain.
L-AP4 is a selective group III metabotropic glutamate receptor (mGluR) agonist. It also acts as an agonist at the quisqualate-sensitized AP6 site in hippocampus...
Ro 01-6128 is a positive allosteric modulator of mGluR1 that potentiates glutamate-induced calcium release (EC50 = 104 nM). Ro 01-6128 activates ERK1/2 phosphor...
EGLU is a group II mGluR antagonist and also a selective antagonist of presynaptically-mediated (1S,3S)-ACPD-induced depression of motoneuron excitation in neon...