|Description||Acarbose sulfate is an anti-diabetic drug used to treat type 2 diabetes mellitus and, in some countries, prediabetes. It is an inhibitor of alpha glucosidase, an enteric enzyme that releases glucose from larger carbohydrates. Acarbose sulfate decreased the Fasting Blood Glucose of DM Rats. The fasting blood glucose (FBG) in the acarbose-treated group decreased significantly at week 2 (P<0.05), week 4 (P<0.05), week 6 (P<0.05), and week 8 (P<0.05) compared to the DM group.|
|Synonyms||Bay-g 5421 sulfate; BAY g 5421 sulfate|
CDK2, a member of the eukaryotic S/T protein kinase family, catalyzes the phosphoryl transfer of ATP γ-phosphate to serine or threonine hydroxyl (denoted as S0/...
BVT-14225 is a highly selective 11β-Hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor(IC50= 52 nM), which is 1,000 fold lower than that for 11β-HSD2.
DIBA, a benzamide derivative, has been found to be an ER zinc finger inhibitor that could be significant in studies of breast cancers.
XEN445 is a potent and selective endothelial lipase inhibitor with IC50 of 0.237 μM.
Lidocaine hydrochloride is the first amino amide–type local anesthetic and antiarrhythmic drug, which has anti-inflammatory properties in vitro and in vivo. It ...
Ro 48-8071 fumarate
Ro 48-8071 is an orally active cholesterol synthesis inhibitor or a 2,3-oxidosqualene:lanosterol cyclase (OSC) inhibitor. OSC (EC 220.127.116.11) represents a unique ...
AVN-944 (VX-944) is an orally available, synthetic small molecule with potential antineoplastic activity. AVN944 inhibits inosine monosphosphate dehydrogenase (...
VU6001221 is a choline transporter (CHT) inhibitor (IC50 value of 270 nM) with comparable potency for choline uptake inhibition as ML352, as well as improved PK...