|Description||AC410 is a Janus kinase 2 (JAK2) inhibitor with Kd of 0.18 nM. AC410 is selective for JAK2 and Kd is 2.5 nM for JAK1 and 5nM for JAK3. Phase I for the treatment of Autoimmune disorders and Inflammation is on-going.|
|Solubility||Soluble in DMSO|
|Application||Autoimmune disorders; Inflammation|
|Quality Standard||In-house standard|
|Shelf Life||2 month in rt, long time|
|Current Developer||Daiichi Sankyo Company|
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