AC260584 - CAS 560083-42-3
Category: Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C20H29FN2O2
Molecular Weight:
348.45
COA:
Inquire
Targets:
mAChR
Description:
AC260584 is a potent and selective muscarinic M₁ receptor allosteric agonist (pEC50= 7.6). Studies indicated that AC260584 has a behavioral profile consistent with antipsychotic-like efficacy with the potential to improve cognitive performance and shows reduced liability for extrapyramidal symptoms.
Publictions citing BOC Sciences Products
  • >> More
Brife Description:
A potent and selective muscarinic M₁ receptor agonist (pEC50= 7.6)
Synonyms:
4-[3-(4-butylpiperidin-1-yl)propyl]-7-fluoro-1,4-benzoxazin-3-one; 4-(3-(4-butylpiperidin-1-yl)propyl)-7-fluoro-4H-benzo(1,4)oxazin-3-one; AC 260584; AC-260584; AC260584
Solubility:
10 mM in DMSO
Storage:
Store in a cool and dry place (or refer to the Certificate of Analysis).
MSDS:
Inquire
Boiling Point:
525.6±50.0 ℃ at 760 Torr
Density:
1.098±0.06 g/cm3
InChIKey:
BWAKMLKESHKOHK-UHFFFAOYSA-N
InChI:
1S/C20H29FN2O2/c1-2-3-5-16-8-12-22(13-9-16)10-4-11-23-18-7-6-17(21)14-19(18)25-15-20(23)24/h6-7,14,16H,2-5,8-13,15H2,1H3
Canonical SMILES:
CCCCC1CCN(CC1)CCCN2C(=O)COC3=C2C=CC(=C3)F
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

Related mAChR Products


CAS 62-97-5 Diphemanil Methylsulfate

Diphemanil Methylsulfate
(CAS: 62-97-5)

Diphemanil Methylsulfate is a quaternary ammonium anticholinergic.It binds muscarinic acetycholine receptors (mAchR).

CAS 50-34-0 Propantheline Bromide

Propantheline Bromide
(CAS: 50-34-0)

Propantheline Bromide is an antimuscarinic agent used as an antispasmodic for the treatment of ulcers.

GYKI-46903 HCl
(CAS: 142999-59-5)

GYKI-46903 is a Muscarinic M3 receptor and Serotonin 3 receptor antagonist. In displacement studies, the pIC50 values of GYKI-46903 against [3H]granisetron bind...

CAS 55869-99-3 Anisodamine

Anisodamine
(CAS: 55869-99-3)

Anisodamine is a alkaloid shown to be a weak antagonist of α1-adrenoceptors, blocking WB-4101 and clonidine by binding in brain membrane preparations.

CAS 148-72-1 pilocarpine nitrate

pilocarpine nitrate
(CAS: 148-72-1)

pilocarpine nitrate is a non-selective muscarinic receptor agonist that can be used to treat glaucoma.

CAS 101-31-5 Hyoscyamine

Hyoscyamine
(CAS: 101-31-5)

Hyoscyamine is an AChR inhibitor with IC50 of 7.5 nM.

CAS 131986-45-3 Xanomeline

Xanomeline
(CAS: 131986-45-3)

Xanomeline is a Muscarinic M1 and M4 receptor agonist under the development of Eli Lilly, though it is also known to act as a M5 receptor antagonist. Xanomeline...

CAS 1227923-29-6 MK-7622

MK-7622
(CAS: 1227923-29-6)

MK-7622 is a cholinesterase inhibitor under evaluation for the treatment of Alzheimer's disease. No studies have been published on this compound in the peer-rev...

PQCA
(CAS: 1144504-35-7)

This active molecular is a muscarinic M1 receptor positive allosteric modulator which is able to improve cognitive measures in rat and rhesus monkeys. PQCA is v...

CAS 242478-38-2 Solifenacin succinate

Solifenacin succinate
(CAS: 242478-38-2)

Solifenacin is a competitive cholinergic receptor antagonist.Solifenacin succinate is a urinary antispasmodic of the antimuscarinic class.

CAS 60-31-1 Acetylcholine Chloride

Acetylcholine Chloride
(CAS: 60-31-1)

Acetylcholine is an organic molecule that acts as a neurotransmitter in many organisms, including humans.

CAS 1159101-48-0 Tarafenacin D-tartrate

Tarafenacin D-tartrate
(CAS: 1159101-48-0)

Tarafenacin is a highly selective M3 muscarinic receptor antagonist (Ki=0.19 nM), ~200 fold selectivity over M2 receptor.

CAS 153504-70-2 Cevimeline hydrochloride hemihydrate

Cevimeline hydrochloride hemihydrate
(CAS: 153504-70-2)

Cevimeline is a muscarinic M1 and M3 receptor agonist. Cevimeline stimulates secretion by the salivary glands and is used to treat the symptoms of dry mouth. Ce...

CAS 674-38-4 Bethanechol

Bethanechol
(CAS: 674-38-4)

Bethanechol, a synthetic ester structurally and pharmacologically related to acetylcholine, is a selective muscarinic receptor stimulant used to increase smooth...

CAS 1235-82-1 Biperiden Hydrochloride

Biperiden Hydrochloride
(CAS: 1235-82-1)

Biperiden hydrochloride is antiparkinsonian; non-selective muscarinic receptor antagonist. Biperiden is used for the adjunctive treatment of all forms of Parkin...

CAS 207679-81-0 (R)-5-Hydroxymethyl tolterodine

(R)-5-Hydroxymethyl tolterodine
(CAS: 207679-81-0)

5-hydroxymethyl tolterodine produces a competitive and concentration-dependent inhibition of carbachol-induced contraction of guinea-pig isolated urinary bladde...

CAS 84504-69-8 Irsogladine maleate

Irsogladine maleate
(CAS: 84504-69-8)

Irsogladine is a PDE4 inhibitor and muscarinic acetylcholine receptor binder. It inhibits bFGF-induced angiogenesis in wild-type, tPA-knockout, and uPA-knockout...

CAS 113-69-9 Benzquinamide Hydrochloride

Benzquinamide Hydrochloride
(CAS: 113-69-9)

Benzquinamide hydrochloride is an antiemetic compound with antihistaminic, anticholinergic and sedative properties. The mechanism of action is not quite sure an...

CAS 77-19-0 Dicycloverine (Dicyclomine)

Dicycloverine (Dicyclomine)
(CAS: 77-19-0)

Dicycloverine, also known as dicyclomine, is an anticholinergic that blocks muscarinic receptors.

CAS 139886-04-7 Milameline hydrochloride

Milameline hydrochloride
(CAS: 139886-04-7)

Milameline is a non-selective muscarinic acetylcholine receptor partial agonist at all receptor subtypes (Ki values are 2.3, 2.4, 3.6, 3.8 and 4.3 μM for hM1, h...

Chemical Structure

CAS 560083-42-3 AC260584

Quick Inquiry

Verification code

Featured Items