Ac-VEID-AMC - CAS 219137-97-0
Molecular Formula:
C32H43N5O11
Molecular Weight:
673.7
COA:
Inquire
Application\Fluorophore:
Fluorescent Enzyme Substrates
Description:
Ac-VEID-AMC is a fluorogenic substrate for caspase-6 and related proteases including caspase-8. Caspase activity can be quantified by fluorescent detection of free AMC (7-amino-4-methylcoumarin), which is excited at 340-360 nm and emits at 440-460 nm.
Sequence:
Ac-Val-Glu-Ile-Asp-AMC
Purity:
≥95%
Appearance:
Solid Powder
Synonyms:
N-Acetyl-Val-Glu-Ile-Asp-7-amido-4-Methylcoumarin; N-acetyl-L-valyl-L-α-glutamyl-L-isoleucyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-L-α-asparagine
Storage:
Store at -20°C
MSDS:
Inquire
Excitation:
340-360 nm
Emission:
440-460 nm
InChIKey:
QMXIJZDGCJEANV-YPBMFZGESA-N
InChI:
InChI=1S/C32H43N5O11/c1-7-16(4)28(37-29(44)21(10-11-24(39)40)35-31(46)27(15(2)3)33-18(6)38)32(47)36-22(14-25(41)42)30(45)34-19-8-9-20-17(5)12-26(43)48-23(20)13-19/h8-9,12-13,15-16,21-22,27-28H,7,10-11,14H2,1-6H3,(H,33,38)(H,34,45)(H,35,46)(H,36,47)(H,37,44)(H,39,40)(H,41,42)/t16-,21-,22-,27-,28-/m0/s1
Canonical SMILES:
CCC(C)C(C(=O)NC(CC(=O)O)C(=O)NC1=CC2=C(C=C1)C(=CC(=O)O2)C)NC(=O)C(CCC(=O)O)NC(=O)C(C(C)C)NC(=O)C
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Chemical Structure

CAS 219137-97-0 Ac-VEID-AMC

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