Ac-DNLD-AMC - CAS 958001-92-8
Molecular Formula:
C30H38N6O12
Molecular Weight:
674.7
COA:
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Application\Fluorophore:
Fluorescent Enzyme Substrates
Description:
Ac-DNLD-AMC is a fluorogenic substrate for caspase-3. It is cleaved by caspase-3 to release the fluorescent moiety 7-amino-4-methylcoumarin (AMC), which can be used to quantify caspase-3 activity.
Sequence:
Ac-Asp-Asn-Leu-Asp-MCA
Purity:
≥95%
Synonyms:
N-Acetyl-Asp-Asn-Leu-Asp-7-amido-Methylcoumarin; N-acetyl-L-α-aspartyl-L-asparaginyl-L-leucyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-L-α-asparagine
Storage:
Store at -20°C
MSDS:
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InChIKey:
IBRRXVTUFUKLDZ-TUFLPTIASA-N
InChI:
InChI=1S/C30H38N6O12/c1-13(2)7-18(34-29(46)19(10-23(31)38)35-30(47)20(11-24(39)40)32-15(4)37)28(45)36-21(12-25(41)42)27(44)33-16-5-6-17-14(3)8-26(43)48-22(17)9-16/h5-6,8-9,13,18-21H,7,10-12H2,1-4H3,(H2,31,38)(H,32,37)(H,33,44)(H,34,46)(H,35,47)(H,36,45)(H,39,40)(H,41,42)/t18-,19-,20-,21-/m0/s1
Canonical SMILES:
CC1=CC(=O)OC2=C1C=CC(=C2)NC(=O)C(CC(=O)O)NC(=O)C(CC(C)C)NC(=O)C(CC(=O)N)NC(=O)C(CC(=O)O)NC(=O)C
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Chemical Structure

CAS 958001-92-8 Ac-DNLD-AMC

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