|Description||ABT670 is a drug which acts as a potent, superior orally bioavailable dopamine agonist selective for the D4 subtype. It was used as a possible treatment for erectile dysfunction.|
|Solubility||Soluble in DMSO, not in water|
|Application||ABT670 was used as a possible treatment for erectile dysfunction.|
|Quality Standard||In-house standard|
|Boiling Point||578.2±50.0 °C | Condition: Press: 760 Torr|
|Melting Point||177-180 °C|
|Density||1.19±0.1 g/cm3 | Condition: Temp: 20 °C Press: 760 Torr|
Droperidol is a potent antagonist of dopamine subtype 2 receptors in the limbic system.
Vanoxerin is a dopamine uptake inhibitor. It is potentially used for the treatment of atrial fibrillation.
Pramipexole (Mirapex) is a partial/full D2S, D2L, D3, D4 receptor agonist with a Ki of 3.9, 2.2, 0.5 and 5.1 nM for D2S, D2L, D3, D4 receptor, respectively.
Neuromedin N is a potent modulator of dopamine D2 receptor agonist which binds in rat neostriatal membranes. It produced a significant concentration-related inc...
Ziprasidone is a combined 5-HT (serotonin) and dopamine receptor antagonist like other atypical antipsychotic agents. Ziprasidone targets dopamine neurotransmis...
The hydrochloride salt form of Adrogolide,a quinoline derivative, has been found to be a dopamine D1 receptor agonist that was once studied in Parkinson's disea...
Aplindore Fumarate is a partial agonist selective for the dopamine receptor D2 used in the therapeutic treatment of Parkinson Disease and restless legs syndrome...
PD-118440 is a dopamine antagonist. It was identified as orally active dopamine (DA) agonists with pronounced central nervous system effects in tests including ...
Dexmethylphenidate HCl, a synthetic sympathomimetic controlled amine with CNS stimulating properties used most commonly in the treatment of attention-deficit di...
GSK598809 is a selective Dopamine D3 receptor antagonist originated by GlaxoSmithKline. It may decrease the rewarding effects of contextual cues associated with...
Oxidopamine hydrochloride, also called as 6-OHDA, is a selective catecholaminergic neurotoxin that selectively destroy dopaminergic and noradrenergic neurons in...
1H-3-Benzazepine-7,8-diol,6-chloro-2,3,4,5-tetrahydro-1-phenyl-3-(2-propen-1-yl)-, hydrobromide (1:1) is a synthetic compound belongs to the benzazepine class ....
Thiethylperazine is a dopamine receptor antagonist It is an antiemetic of the phenothiazine class. Though it was never licensed or used as an antipsychotic, it ...
Chlorpromazine HCl is a dopamine and potassium channel inhibitor with IC50 of 6.1 and 16 μM for inward-rectifying K+ currents and time-independent outward curre...
Fenoldopam is a selective D1 receptor partial agonist, binds to α2-adrenoceptors, increasing renal blood flow used as an antihypertensive agent.
Metoclopramide hydrochloride hydrate
Metoclopramide hydrochloride hydrate is a dopamine D2 antagonist used to treat nausea and vomitin.
Dexpramipexole, also known as R-(+)-Pramipexole, is one of the impurities of pramipexole(USP D). It coule be used as a negative control in the research of dopam...
ABT-724 is a dopamine D4 agonist originated by Abbott Laboratories with EC50 value of 12.4 nM. In Dec 2007, Phase-II for Erectile dysfunction was discontinued i...
The hydrochloride salt form of Iloperidone which is a antagonist of both D2 and 5-HT2 receptor and has been commonly used against schizophrenia. IC50: 10-100 nm...
Prochlorperazine is a dopamine D2 receptor antagonist. It belongs to the phenothiazine class of antipsychotic agents and can be used for the antiemetic treatmen...