|Targets||Platelet-activating factor receptor (PAF-R)|
|Description||ABT-491, an imidazopyridine derivative, has been found to be a PAF receptor antagonist that was once studied against allergic rhinitis.|
|Synonyms||ABT-491 free base; UNII-AYB44L739V; CHEMBL369225; ABT 491; 4-ethynyl-3-[3-fluoro-4-[(2-methylimidazo[4,5-c]pyridin-1-yl)methyl]benzoyl]-N,N-dimethylindole-1-carboxamide|
|Storage||Store in a cool and dry place and at 0 - 4 °C for short term (days to weeks) or -20 °C for long term (months to years).|
|Quality Standard||In-house standard|
ABT-491 Hydrochloride is a potent, selective and orally active platelet-activating factor receptor (PAF-R) antagonist (Ki = 0.6 nM in human platelets).
This active molecular is a dihydropyridine Platelet-Activating Factor (PAF) antagonist under the development of Pfizer. In Sep 2015, treatment for Asthma in USA...
ABT-491, an imidazopyridine derivative, has been found to be a PAF receptor antagonist that was once studied against allergic rhinitis.
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