|Description||Arecaidine But-2-ynyl Ester Tosylate (ABET) is a potent and selective agonist of M2 recceptors in the atrium versus those in the ileum.|
|Synonyms||Arecaidine but-2-ynyl ester tosylate; N-Methyl-1'2'5'6-tetrahydropyridine-3-carboxylic acid but-2-ynyl ester tosylate|
|Melting Point||>127°C (dec.)|
AQ-RA 741 has been found to be a muscarinic M2 receptor antagonist and could probably be used in the development of bronchodilator anti-muscarinic agent.
A selective muscarinic receptor stimulant, used to treat cerebral palsy.
Arecaidine propargyl ester tosylate
Arecaidine propargyl ester tosylate is a potent muscarinic receptor agonist. It displays some selectivity for cardiac versus ileal M2 receptors.
W-84 dibromide is a potent allosteric modulator of muscarinic M2 receptors. W-84 dibromide has been shown to stabilize cholinergic antagonist-receptor complexes...
Aclidinium Bromide(LAS 34273; LAS-W 330) is a long-acting, inhaled muscarinic antagonist as a maintenance treatment for chronic obstructive pulmonary disease (C...
Propantheline Bromide is an antimuscarinic agent used as an antispasmodic for the treatment of ulcers.
Bethanechol, a synthetic ester structurally and pharmacologically related to acetylcholine, is a selective muscarinic receptor stimulant used to increase smooth...
Nitrocaramiphen hydrochloride is a mAChR M1 selective muscarinic antagonist, which exhibits 71-fold selectivity for M1 over M2.
5-hydroxymethyl tolterodine produces a competitive and concentration-dependent inhibition of carbachol-induced contraction of guinea-pig isolated urinary bladde...
Muscarinic M3 receptor antagoinst. Used in treatment of urinary incontinence.
VU 0255035 is a highly selective M1 muscarinic acetylcholine receptor antagonist (Ki = 14.87 nM) with 75-fold greater selectivity for the M1 orthosteric site ov...
AF-DX 384 has been found to be a mAChR M2/M4 selective antagonist.
Cevimeline hydrochloride hemihydrate
Cevimeline is a muscarinic M1 and M3 receptor agonist. Cevimeline stimulates secretion by the salivary glands and is used to treat the symptoms of dry mouth. Ce...
Homatropine Bromide is an muscarinic AChR antagonist, inhibits endothelial and smooth muscle muscarinic receptors of WKY-E and SHR-E with IC50 of 162.5 nM and 1...
Biperiden is an antiparkinsonian agent, which is the selective central M1 cholinoreceptors blocker. It is used for the adjunctive treatment of all forms of Park...
Tolterodine has a high affinity and specificity for muscarinic receptors in vitro and it exhibits selectivity for the urinary bladder over salivary glands in vi...
AF-DX 116 has been found to be a selective mAChR M2 antagonist.
Flavoxate is an anticholinergic with antimuscarinic effects. Its muscle relaxant properties may be due to a direct action on the smooth muscle rather than by an...
Oxybutynin is an anticholinergic medication used to relieve urinary and bladder difficulties.
Pilocarpine HCl is a nonselective muscarinic acetylcholine receptor agonist used to produce an experimental model of epilepsy.