|Description||Arecaidine But-2-ynyl Ester Tosylate (ABET) is a potent and selective agonist of M2 recceptors in the atrium versus those in the ileum.|
|Synonyms||Arecaidine but-2-ynyl ester tosylate; N-Methyl-1'2'5'6-tetrahydropyridine-3-carboxylic acid but-2-ynyl ester tosylate|
|Melting Point||>127°C (dec.)|
(+)-Muscarine iodide is a muscarinic receptor agonist with activity similar to that of acetylcholine, involved in the production of gastric acid.
Muscarinic receptors are G protein-coupled acetylcholine receptors that play diverse roles. Xanomeline oxalate is a potent agonist of muscarinic acetylcholine r...
MK-7622 is a cholinesterase inhibitor under evaluation for the treatment of Alzheimer's disease. No studies have been published on this compound in the peer-rev...
Biperiden is an antiparkinsonian agent, which is the selective central M1 cholinoreceptors blocker. It is used for the adjunctive treatment of all forms of Park...
Imidafenacin(KRP-197; ONO-8025) is a potent and selective inhibitor of M3 receptors with Kb of 0.317 nM; less potent for M2 receptors(IC50=4.13 nM).
Irsogladine is a PDE4 inhibitor and muscarinic acetylcholine receptor binder. It inhibits bFGF-induced angiogenesis in wild-type, tPA-knockout, and uPA-knockout...
VU 0357017 hydrochloride
The hydrochloride salt form of VU0357017 which is a selective M1 agonists and has been found to be probably effective in the treatment of hippocampal-dependent ...
Pyrithioxin dihydrochloride, a pyridine thiol derivative, is a nootropic which could be used in the treatment of sequelae of brain trauma, encephalitis and meni...
Tubocurarine hydrochloride pentahydrate
Tubocurarine is a toxic alkaloid. It is an acetylcholine receptor (AChR)-blocking agent. Tubocurarine is now rarely used as an adjunct for clinical anesthesia b...
Glycopyrrolate bromide is a muscarinic competitive antagonist used as an antispasmodic.
5-hydroxymethyl tolterodine produces a competitive and concentration-dependent inhibition of carbachol-induced contraction of guinea-pig isolated urinary bladde...
Benzhexol HCl is an anticholinergic tertiary amine used to treat parkinsonism and the extrapyramidal side effects of anti-psychotic drugs.
Umeclidinium bromide(GSK573719A) is a muscarinic receptor antagonist which is useful in treatment of chronic obstructive pulmonary disease (COPD).
VU 0029767 is a positive allosteric modulator of M1, a member of the muscarinic acetylcholine family of GPCRs (mAChRs). VU 0029767 enhances the competitive effe...
Bethanechol, a synthetic ester structurally and pharmacologically related to acetylcholine, is a selective muscarinic receptor stimulant used to increase smooth...
VU0152100 is a selective and positive allosteric modulators of M4 receptor. It has shown a potent positive allosteric modulators that increase the response of t...
Camylofine is an antimuscarinic with both anticholinergic action as well as direct smooth muscle action. It can be used to treat the pain caused by smooth muscl...
Scopolamine is an anti-muscarinic and cholinolytic alkaloid that inhibits parasympathetic-cholinergic system. The central effects include hallucinations, disori...
Scopolamine HBr is a competitive muscarinic acetylcholine receptor with an IC50 of 55.3 nM.
Nitrocaramiphen hydrochloride is a mAChR M1 selective muscarinic antagonist, which exhibits 71-fold selectivity for M1 over M2.