|Description||Abafungin is a broad-spectrum antifungal agent with a novel mechanism of action originated by York Pharma. In Aug 2009, Phase-III for Dermatomycoses in Japan and Europe was discontinued. At the same time, preclinical for Onychomycosis in United Kingdom was discontinued.|
|Appearance||White to yellow solid|
|Solubility||Soluble in DMSO|
|Quality Standard||In-house standard|
|Shelf Life||2 month in rt, long time|
|Boiling Point||533.6ºC at 760mmHg|
|Current Developer||Originator:York Pharma|
Sarolaner is an antiparasitic agent. It is used as veterinary drug.
CCF-642 is a protein disulfide isomerase (PDI) inhibitor that exhibits 100-fold higher potency than PACMA 31 (by di-E-GSSG assay) via an alternative mode of act...
FE-999024, a dipeptide compound, has been found to be a kallikrein inhibitor that was once studied in pancreatitis by Ferring Pharmaceuticals.
Faropenem potassium is an orally active beta-lactam antibiotic. It is a prodrug of Faropenem and belongs to the penem group. It is resistant to some forms of ex...
Sulisobenzoneis a UV filter which protects the skin from damage by UVB and short-wave UVA ultraviolet light
Ajugol is an iridiod glucoside isolated from the roots of Rehmannia glutinosa.
Ginsenoside Rb3, a natural triterpenoid saponin, possesses the effect against isoproterenol-induced myocardial injury and heart function impairment, and that th...
Anle138b is a novel fluorescent oligomer modulator and an aggregation inhibitor. In vitro, anle138b blocked the formation of pathological aggregates of prion pr...
Mesna is converted to a free thiol compound in the kidney, where it binds to and inactivates acrolein and other urotoxic metabolites of ifosfamide and cyclophos...
Cyclo(RADfK) is a selective α(v)β(3) integrin ligand. It has been used for research, therapy, and diagnosis of neoangiogenesis. It is also used as a negative co...
Lapaquistat acetate, also referred as TAK475, is a squalene synthase inhibitor. As a cholesterol-lowering drug, Lapaquistat acetate decreased plasma cholesterol...
Bloom (BLM) helicase is a DNA unwinding enzyme important for DNA repair in the homologous recombination pathway. Mutations of the BLM gene result in reduced BLM...
Berubicin hydrochloride is hydrochloride salt of the anthracycline derivative berubicin as a topoisomerase II inhibitor with activity in ependymoma.
1,2,2,6,6-Pentamethylpiperidine is a ganglion-blocking drug. It is one of the most strongly basic tertiary amine. It is ued as an oral treatment for hypertensio...
CCT007093 is a potent PPM1D inhibitor or WIP1 inhibitor that selectively reduces viability of human tumour cell lines
Arbidol is an antiviral agent using for the treatment of influenza infection in Russia and China. It inhibits membrane fusion and prevents contact between the v...
GLPG-1690, an imidazopyridine derivative, has been found to be a ENPP2 protein inhibitor that could probably be effective as an anti-inflammatory agent and is u...
Benazepril is a drug of the angiotensin-converting enzyme (ACE) inhibitor used to treat high blood pressure.
MK 0927 is a potential bio-active agent., but no detail information has been published yet.