|Description||A 987306 is a potent histamine H4 receptor antagonist (pKi = 8.24 and 8.47 in human and rat H4 receptors, respectively) with 162-, 620-, and > 1600-fold selectivity over human H3, H1 and H2 receptors. It suppresses zymosan-induced neutrophil reflux and attenuates thermal hypersensitivity in vivo (ED50 = 42 μmol/kg, ip).|
|Brife Description||histamine H4 receptor antagonist|
|Purity||≥98% by HPLC|
A 331440 dihydrochloride
A 331440 dihydrochloride is a histamine H3 receptor antagonist (Ki = 21.7 and 22.7 nM for rat and human H3 receptors, respectively). A 331440 reduces weight in ...
Famotine hydrochloride is a histamine H2 receptor antagonist. lt has no effect on the cytochrome P450 enzyme system, and does not appear to interact with other ...
Roxatidine Acetate HCl
Roxatidine Acetate HCl is a specific and competitive histamin H2 receptor antagonist.
This active molecular is a imidazolylpropylguanidine type compound as a hH4R agonist (histamine H4 receptor agonist) showing negligible hH1R and hH2R activities...
Immethridine dihydrobromide is the dihydrobromide salt of immethridine, which is a highly selective, potent and novel histamine H3 receptor agonist with pEC50 v...
Alcaftadine(R89674) is a H1 histamine receptor antagonist, which is used to prevent eye irritation brought on by allergic conjunctivitis.
Azelastine HCl is a potent, second-generation, selective, histamine antagonist. It inhibits histamine via competing with histamine for the H1 receptor.
Alimemazine is a phenothiazine derivative as a Histamine Receptor antagonist. It can be used as an antipruritic . It also acts as a sedative, hypnotic, and anti...
Fexofenadine inhibits histamine H1 receptor with IC50 of 246 nM.
VUF 5681 dihydrobromide
VUF 5681 dihydrobromide is a potent histamine H3 receptor silent antagonist (pKi = 8.35).
Bepotastine is a histamine H1 receptor antagonist. Bepotastine has been approved in Japan for the treatment of allergic rhinitis and uriticaria/puritus.
Emedastine is a H1 receptor antagonist. It is a second generation antihistamine. Emedastine can block the action of histamine that causes allergic symptoms. It ...
Meclizine is a histamine H1 receptor antagonist used to treat nausea and motion sickness, has anti-histamine, anti-muscarinic and anti-oxidative phosphorylation...
GT 2016 is a high affinity and brain-penetrant histamine H3 receptor antagonist (Ki = 43.8 nM). It displays selectivity against H1 and H2 receptors (IC50 >10 μM...
JNJ 5207852 dihydrochloride
The hydrochloride salt form of JNJ 5207852, which has been found to be a histamine H3 receptor antagonist and could probably be used against obesity.
(S)-(+)-α-Methylhistamine dihydrobromide is the less active enantiomer of histamine H3 receptor agonist R-(-)-α-methylhistamine, with 120-fold less potent than ...
METHDILAZINE HYDROCHLORIDE (200 MG)
This active molecular is a first-generation antihistamine and belongs to phenothiazine class. Methdilazine Hydrochloride is a Histamine H1 receptor antagonist w...
Astemizole is a potent and orally active nonsedating-type histamine H1 receptor antagonist with IC50 value of 4 nM. It competitively binds to histamine H1 recep...
The ditrifluoroacetate salt form of Carcinine, which is a highly selective histamine H3 receptor antagonist and could act as a natural antioxidant.
KDM5A-IN-1, a pyrrolidine amide compound, is an inhibitor histone demethylases.