|Description||A-92 inhibits the stress response of general control nonderepressible 2 kinase (GCN2 or EIF2AK4) (IC50 value of <0.3 μM). It is potentially used as a chemotherapeutic drug for the treatment of cancer.|
|Application||potential chemotherapeutic drug|
TMN 355 is a potent cyclophilin A inhibitor (IC50 = 1.52 nM), displaying 27-fold potency against cyclosporin A.
5S rRNA modificator
5S rRNA modificator is a suitable electrophile for 2’-hydroxyl acylation on structured RNA molecules, yielding accurate structural information comparable to tha...
Gastrin-Releasing Peptide, human
Gastrin-Releasing Peptide, human (GRP), one of the bombesin-like peptide family, is an agonist for the gastrin-releasing peptide receptor (GRPR) and it plays on...
YM 750 is an acyl-CoA:cholesterol acyltransferase (ACAT) inhibitor (IC50 = 0.18 μM), displaying hypocholesterolaemic and antiatherosclerotic activity in vivo.
MK436 is an anti-protozoal drug has been found to be effective against Trypanosoma cruzi infections.
Levobupivacaine HCl, the pure S(-)-enantiomer of bupivacaine, is a reversible neuronal sodium channel inhibitor, used as a long-acting local anesthetic.
GBT-440 is a substituted benzaldehyde compound that can modulate sickle hemoglobin (HbS) for treatment of disorders.
L-Allo-isoleucine, an amino acid compound, has been found to be probably significant in the study of modulating of blood sugar.