A-836339 - CAS 959746-77-1
Catalog number: 959746-77-1
Category: Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C16H26N2O2S
Molecular Weight:
310.45
COA:
Inquire
Targets:
Cannabinoid Receptor
Description:
A-836339 is a synthetic and potent cannabinoid receptor full agonist. It displays a higher affinity for the peripheral CB2 receptor with Ki value of 0.64 nM over the central CB1 receptor with Ki of 270 nM in both human and rat in radioligand binding assays. It also displays analgesic, anti-inflammatory, and anti-hyperalgesic effects in mice at low doses. It exhibits a profile devoid of significant affinity at other G-protein-coupled receptors and ion channels. It has also demonstrated efficacies in the chronic constrain injury (CCI) model of neuropathic pain, skin incision, and capsaicin-induced secondary mechanical hyperalgesia models. It is intended for forensic and research applications. It was suggested to be for human consumption. It was developed by Abbott Laboratories.
Publictions citing BOC Sciences Products
  • >> More
Purity:
>99 %
Appearance:
Light yellow to yellow Solid
Synonyms:
N-[3-(2-methoxyethyl)-4,5-dimethyl-1,3-thiazol-2-ylidene]-2,2,3,3-tetramethylcyclopropane-1-carboxamide;CyclopropanecarboxaMide, N-[3-(2-Methoxyethyl)-4,5-diMethyl-2(3H)-thiazolylidene]-2,2,3,3-tetraMethyl-, [N(Z)]-;1-(Tetrahydropyran-4-ylMethyl)-1H-indol-3-yl]-(2,2,3,5-tetraMethylcyclopropyl)Methanone
Solubility:
DMSO: ≥ 12 mg/mL
Storage:
-20°C Freezer
MSDS:
Inquire
Application:
A-836339 displays analgesic, anti-inflammatory, and anti-hyperalgesic effects. It was suggested to be for human consumption.
Quality Standard:
In-house standard
Shelf Life:
2 month in rt, long time
Quantity:
Grams to Kilograms
Boiling Point:
388.4±44.0 °C | Condition: Press: 760 Torr
Density:
1.14±0.1 g/cm3 | Condition: Temp: 20 °C Press: 760 Torr
InChIKey:
JKGIMVBQKSRTGX-UHFFFAOYSA-N
InChI:
InChI=1S/C16H26N2O2S/c1-10-11(2)21-14(18(10)8-9-20-7)17-13(19)12-15(3,4)16(12,5)6/h12H,8-9H2,1-7H3
Canonical SMILES:
CC1=C(SC(=NC(=O)C2C(C2(C)C)(C)C)N1CCOC)C
Current Developer:
A-836339 was developed by Abbott Laboratories.
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

Related Cannabinoid Receptor Products


CAS 168273-06-1 Rimonabant

Rimonabant
(CAS: 168273-06-1)

Rimonabant is a selective antagonist of CB1 with IC50 of 13.6 nM and EC50 of 17.3 nM in hCB1 transfected HEK 293 membrane.

CAS 861151-12-4 Rosonabant

Rosonabant
(CAS: 861151-12-4)

Rosonabant is a CB1 receptor antagonist/inverse agonist originated by Esteve. It is an appetite suppressant for the treatment of obesity. But development of the...

CAS 432047-72-8 CB-13

CB-13
(CAS: 432047-72-8)

CB-13 is a dual agonist of the CB1 (IC50 = 15 nM) and CB2 (IC50 = 98 nM) receptors, displays antihyperalgesic activity in a rat model of neuropathic pain with n...

CAS 220556-69-4 ACEA

ACEA
(CAS: 220556-69-4)

ACEA is a selective cannabinoid receptor 1 (CB1R) agonist (Ki = 1.4 nM) with much higher affinity over CB2R. CB1 receptors are mainly expressed in the central a...

Levonantradol hydrochloride
(CAS: 70222-86-5)

Levonantrado is a synthetic cannabinoid analog of dronabinol developed by Pfizer in the 1980s. Levonantrado is around 30x more potent than THC, and exhibits ant...

CB1-IN-1
(CAS: 1429239-98-4)

CB1-IN-1 is an antagonist of cannabinoid receptor type 1 (CB1R) located in the peripheral nervous system, which may be significant for pain modulation.

CAS 1446-61-3 Leelamine

Leelamine
(CAS: 1446-61-3)

Leelamine, a diterpene molecule, has weak affinity for the human central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors. Leelamine is also a PDK(p...

CAS 212188-60-8 BAY 38-7271

BAY 38-7271
(CAS: 212188-60-8)

BAY 38-7271, also called as KN 38-7271, is a cannabinoid receptor agonist with analgesic and neuroprotective effects. The doses of BAY 38-7271 in animals needed...

CAS 686344-29-6 Otenabant (CP-945,598)

Otenabant (CP-945,598)
(CAS: 686344-29-6)

Otenabant, also known as CP-945,598, is a drug which acts as a potent and highly selective CB1 antagonist. It was developed by Pfizer for the treatment of obesi...

CAS 131543-23-2 WIN 55212-2 mesylate

WIN 55212-2 mesylate
(CAS: 131543-23-2)

The mesylate salt form of WIN 55212-2, an aminoalkylindole derivative, is a CB receptor agonist and could be effective against some inflammatory reponse. IC50: ...

CAS 464213-10-3 Ibipinabant

Ibipinabant
(CAS: 464213-10-3)

Ibipinabant is a potent and selective CB1 receptor antagonist with Ki values of 7.8 and 7,943 nM for CB1 and peripheral cannabinoid (CB2), respectively.

CAS 1048973-47-2 MDA 19

MDA 19
(CAS: 1048973-47-2)

MDA 19, a benzohydrazide derivative, has been found to be a CB2 receptor agonist and could be useful in reducting the Attenuates tactile allodynia of rats. IC50...

CAS 959746-77-1 A-836339

A-836339
(CAS: 959746-77-1)

A-836339 is a synthetic and potent cannabinoid receptor full agonist. It displays a higher affinity for the peripheral CB2 receptor with Ki value of 0.64 nM ove...

CAS 871819-90-8 GSK554418A

GSK554418A
(CAS: 871819-90-8)

GSK-554418A is a azaindole Cannabinoid receptor type 2 (CB2) agonist. It can be used for the treatment of chronic pain.

CAS 358970-97-5 Drinabant

Drinabant
(CAS: 358970-97-5)

Drinabant is a highly potent, selective antagonist for the CB1 receptor with Ki values of 0.16-0.44 nM.

CAS 183232-66-8 AM251

AM251
(CAS: 183232-66-8)

AM251 block the inhibitory effects of endocannabinoids and synthetic cannabinoid agonists on transmitter release through an action at presynaptic cannabinoid 1 ...

AM-1220
(CAS: 134959-64-1)

AM-1220 is a selective cannabinoid receptor CB1 agonist , with about 19x selectivity for CB1 over the related CB2 receptor originated by Sterling Winthrop. In O...

AM 1714
(CAS: 335371-37-4)

AM 1714, a synthetic cannabimimetic indole derivative, is a potent and selective agonist for the cannabinoid receptor.

CAS 701977-09-5 Taranabant

Taranabant
(CAS: 701977-09-5)

Taranabant is a cannabinoid 1 receptor inverse agonist ( IC50 =0.3 nM).

CAS 406205-74-1 BAY 59-3074

BAY 59-3074
(CAS: 406205-74-1)

Bay 59-3074 is a novel, selective CB1/CB2 receptor partial agonist(Ki values are 48.3 and 45.5 nM at human CB1 and CB2 receptors respectively).

Chemical Structure

CAS 959746-77-1 A-836339

Quick Inquiry

Verification code

Featured Items