A-83-01 - CAS 909910-43-6
Catalog number:
909910-43-6
Category:
Stem Cell Molecule
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C25H19N5S
Molecular Weight:
421.52
COA:
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Description:
A83-01 is a selective inhibitor of the transforming growth factor-beta (TGF-β) type I receptor ALK5, the Activin/Nodal receptor ALK4, and the nodal receptor ALK7. This molecule is more potent than SB431542 in its inhibition of ALK4, 5, and 7, and only weakly inhibits ALK1, 2, 3, and 6. A83-01 inhibits the TGF-β-induced epithelial-to-mesenchymal transition (EMT) via the inhibition of Smad2 phosphorylation.
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Purity:
0.98
Appearance:
Pale yellow solid
MSDS:
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Application:
Reprogramming, Differentiation
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Chemical Structure

CAS 909910-43-6 A-83-01

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