|Description||A 784168 is a potent and selective TRPV1 antagonist (IC50 = 25 nM for inhibition of TRPV1 activation by 50 nM capsaicin) exhibiting no activity against a range of receptors such as TRPA1, GABA, opioid, and purinergic receptors.|
|Brife Description||TRPV1 antagonist|
|Purity||≥99% by HPLC|
Nonivamide, also called as N-Vanillylnonanamide, a synthetic analogue of Capsaicin isolated from peppers, is a VR1 (TRPV1) agonist.
SAR7334, a TRPC6 inhibitor, could be valuable in studying sorts of diseases related to TRPC.
A 425619 is a potent and selective TRPV1 antagonist (IC50 = 3-9 nM) that inhibits TRPV1 activation by anandamide and N-arachidonoyl-dopamine. A 425619 exhibits ...
CIM 0216 has been found to be a selective TRPM3 agonist and could stimulate the release of insulin from pancreatic islet cells.
The hydrochloride salt form of AMTB, which has been found to be a TRPM8 channel blocker.
AM 404 has been found to be an anandamide transport inhibitor and proved to exhibit effective in activating native and cloned vanilloid receptors.
EIPA is a TRPP3 channel inhibitor (IC50 = 10.5 μM). EIPA also acts as an Na+/H+ exchange inhibitor that suppresses the Na+/H+ exchanger (NHE).
AC 4 is a photoswitchable TRPV1 channel blocker (IC50 = 3.1 μM) that converts TRPV1 channels into photoreceptors.