A 438079 hydrochloride - CAS 899507-36-9
Catalog number:
899507-36-9
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C13H10Cl3N5
Molecular Weight:
342.61
COA:
Inquire
Targets:
Others
Description:
A 438079 hydrochloride is a competitive P2X7 receptor antagonist with pIC50 value of 6.9 for the inhibition of Ca2+ influx in the human recombinant P2X7 cell line. It protects against acetaminophen-induced liver injury by inhibiting p450 isoenzymes, but not by inflammasome activation. It partially but significantly prevented the 6-OHDA-induced depletion of striatal DA stores.
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Purity:
>98 %
Appearance:
Solid powder
Synonyms:
3-[[5-(2,3-Dichlorophenyl)-1H-tetrazol-1-yl]methyl]pyridine hydrochloride;A-438079 HCl;A-438079 hydrochloride
Solubility:
10 mM in DMSO
Storage:
-20°C Freezer
MSDS:
Inquire
Quality Standard:
In-house standard
Shelf Life:
2 month in rt, long time
Quantity:
Milligrams-Grams
Boiling Point:
525.1±60.0 °C | Condition: Press: 760 Torr
Density:
1.49±0.1 g/cm3 | Condition: Temp: 20 °C Press: 760 Torr
InChIKey:
MBTJFFMIPPMRGR-UHFFFAOYSA-N
InChI:
InChI=1S/C13H9Cl2N5.ClH/c14-11-5-1-4-10(12(11)15)13-17-18-19-20(13)8-9-3-2-6-16-7-9;/h1-7H,8H2;1H
Canonical SMILES:
C1=CC(=C(C(=C1)Cl)Cl)C2=NN=NN2CC3=CN=CC=C3.Cl
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

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CAS 899507-36-9 A 438079 hydrochloride

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