|Description||A 438079 hydrochloride is a competitive P2X7 receptor antagonist with pIC50 value of 6.9 for the inhibition of Ca2+ influx in the human recombinant P2X7 cell line. It protects against acetaminophen-induced liver injury by inhibiting p450 isoenzymes, but not by inflammasome activation. It partially but significantly prevented the 6-OHDA-induced depletion of striatal DA stores.|
|Synonyms||3-[[5-(2,3-Dichlorophenyl)-1H-tetrazol-1-yl]methyl]pyridine hydrochloride;A-438079 HCl;A-438079 hydrochloride|
|Solubility||10 mM in DMSO|
|Quality Standard||In-house standard|
|Shelf Life||2 month in rt, long time|
|Boiling Point||525.1±60.0 °C | Condition: Press: 760 Torr|
|Density||1.49±0.1 g/cm3 | Condition: Temp: 20 °C Press: 760 Torr|
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