A 437203 - CAS 220519-06-2
Catalog number:
220519-06-2
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C20H27F3N6OS
Molecular Weight:
456.53
COA:
Inquire
Targets:
Dopamine Receptor
Description:
A 437203 is a selective dopamine (DA) D3 receptor antagonist suited to evaluate the physiological role(s) of D3 receptors. A 437203 shows an approximately 100-fold higher in vitro affinity for dopamine D₃ versus D₂ receptors.
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Purity:
>98%
Appearance:
White Solid
Synonyms:
2-[3-[4-[2-tert-butyl-6-(trifluoromethyl)pyrimidin-4-yl]piperazin-1-yl]propylsulfanyl]-1H-pyrimidin-6-one; 2-(3-(4-(2-tert-butyl-6-trifluoromethylpyrimidin-4-yl)piperazin-1-yl)propylsulfanyl)-3H-pyrimidin-4-one fumarate; A 437203; A-437203; 1160247-85-7; 220519-07-3 (anhydrous); 220519-06-2 (anhydrous free base)
MSDS:
Inquire
Melting Point:
202-204°C
InChIKey:
KXVAICSRMHXLJN-UHFFFAOYSA-N
InChI:
1S/C20H27F3N6OS/c1-19(2,3)17-25-14(20(21,22)23)13-15(26-17)29-10-8-28(9-11-29)7-4-12-31-18-24-6-5-16(30)27-18/h5-6,13H,4,7-12H2,1-3H3,(H,24,27,30)
Canonical SMILES:
CC(C)(C)C1=NC(=CC(=N1)N2CCN(CC2)CCCSC3=NC=CC(=O)N3)C(F)(F)F
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