|Description||9-Anthracenecarboxylic acid is a Cl- transport inhibitor with a moderate to strong inhibitory effect on PKA activated cardiac IcI.|
|Brife Description||chloride channel blocker|
|Purity||≥99% by HPLC|
|Synonyms||Anthracene-9-carboxylic acid; 9-AC|
Lubiprostone is a bicyclic fatty acid metabolite of Prostaglandin E1. It activates ClC-2 and CFTR chloride channels in the gastrointestinal tract, increasing in...
Talniflumate is a calcium-activated chloride channel (CaCC) (hCLCA1/mCLCA3) blocker. It decreases mucin synthesis and release in cell culture and animal models....
9-Anthracenecarboxylic acid is a Cl- transport inhibitor with a moderate to strong inhibitory effect on PKA activated cardiac IcI.
MONNA is a potent TMEM16A (Anoctamin-1) blocker (IC50 = 80 nM) that does not interact with anion channels such as CFTR, ClC‐2 and bestrophin 1. MONNA induces va...
R(+)-IAA-94 is a potent indanyloxyacetic acid blocker as an indanyloxyacetic acid (IAA) inhibitor of chloride channels ( Ki =1 µM.)
DIDS disodium salt
DIDS disodium salt is a stilbene sulfonate that acts as a ClC-Ka chloride channel blocker (IC50 = 100 μM). It blocks the maxi chloride channel in apical membran...
T16Ainh-A01 is a selective inhibitor of Ca2+-dependent Cl- channel (CaCC) transmembrane protein 16A (TMEM16A) (IC50 = 1.8 μM in A253 salivary gland epithelial c...
Lubiprostone, also known as RU-0211, is a medication used for the treatment of chronic constipation of unknown cause in adults, as well as irritable bowel syndr...