|Molecular Formula||C18H19N5O7PS · Na|
|Description||8-pMeOPT-2'-O-Me-cAMP is a specific activator of the exchange protein activated by cAMP (Epac) or cAMP-GEF, which does not activate protein kinase A. It is highly lipophilic, membrane-permeant and stable for PDE.|
|Purity||≥ 98% by HPLC|
|Synonyms||8- (4- Methoxyphenylthio)- 2'- O- methyladenosine- 3', 5'- cyclic monophosphate, sodium salt|
Rp-2'-AHC-cGMPS-Agarose is the PDE-resistant PKG inhibitor Rp-cGMPS immobilized on agarose by an aminohexylcarbamoyl spacer, which can be used in affinity chrom...
2'-TAMRA-AHC-cGMP is a fluorescent cGMP analogue (λexc555 nm, λem580 nm) that can be used for phosphodiesterase studies.
8-CPT-6-Phe-cAMP is a selective activator of protein kinase A (cAMP agonist). It effects against mammalian cyclic nucleotide-dependent phosphodiesterases.
Rp-6-Cl-cPuMPS is a PDE-resistant modulator of protein kinase A that can be modified in position 6.
c[A(2',5')pS[Rp]-A(3',5')pS[Rp]] / Rp,Rp
c[A(2',5')pS[Rp]-A(3',5')pS[Rp]] is a synthetic cyclic dinucleotide with higher stability resisting degradation by phosphodiesterases. It has improved binding a...
4-N3-PET-8-Biotin-11-cGMP is a cGMP analogue used for photoaffinity labelling of cGMP-responsive receptors.
c-(Ap-8-Biotin-11-Gp) is an analogue of the cyclic dinucleotide c-(ApGp). It is a potential tracer in immunoassays and commonly used for affinity chromatography...
2'-NH2-cAMP is often used in affinity chromatography of cAMP and cGMP binding proteins for its amino group used as a ligand, which do not require an intact 2'-O...
5,6-DM-cBIMP is an activator of phosphodiesterase type II and it has a slight activated effect for protein kinase G.
8-Cl-cAMP is a selective cAMP analogue preferring protein kinase A type I. 8-Cl-cAMP has already been in several clinical trials to identify its inhibitory effe...
2'-AEC-cGMP-Agarose is the protein kinase G activator cGMP immobilized on agarose by an aminoethylcarbamoyl spacer, which can be used in affinity chromatography...
2-ADOA-cAMP is a hydrophilic analogue of cAMP, which is used as a ligand in affinity chromatography and can be modified with fluorophores.
2'-AEC-cGMP is a cGMP analogue used for immobilization as an affinity ligand or for coupling of labelling structures such as fluorophores.
Rp-c-diGMPS is an analogue of c-diGMP, the bacterial second messenger, which can be used to study ligand-receptor interactions.