|Molecular Formula||C10H10ClN5O6P · Na|
|Description||8-Cl-cAMP is a selective cAMP analogue preferring protein kinase A type I. 8-Cl-cAMP has already been in several clinical trials to identify its inhibitory effect of growth and differentiation in cultured cancer cell lines.|
|Purity||≥ 99% by HPLC|
|Synonyms||8- Chloroadenosine- 3', 5'- cyclic monophosphate, sodium salt|
8-AHA-2-Cl-cAMP is a selective cAMP analogue that has a preference for side B I of PKA.
4-N3-PET-8-Biotin-11-cGMP is a cGMP analogue used for photoaffinity labelling of cGMP-responsive receptors.
Rp,Sp-c-diAMPSS is an analogue of c-diAMP, the bacterial second messenger, which has higher stability. It can be used to study ligand-receptor interactions.
2'-O-MB-cCMP is a precursor and biologically inactive analogue of cCMP, the putative second messenger nucleotide. cCMP would be released when 2'-O-MB-cCMP is me...
Rp-2'-AEC-cAMPS is an analogue of Rp-cAMPS, the PKA inhibitor, which is used for immobilization as an affinity ligand or for coupling of labelling structures su...
c-diAMP was recognized as a second messenger for signalling DNA integrity in Bacillus subtilisduring sporulation, and an additional purine-based signalling nucl...
Sp-8-Br-PET-cGMPS is an inhibitor of the retinal type cGMP-gated ion channel (cGMP antagonist) as well as a stimulator of cyclic GMP-dependent protein kinase I ...
8-Cl-cAMP-AM is a precursor of 8-Cl-cAMP, the PKA activator. The polar active analogue is released after the metabolism of 8-Cl-cAMP-AM by esterases.
Rp-cCMPS is a PDE-resistant cCMP, the potential second messenger, which inhibits cCMP-binding proteins.
2'-O-Me-c-diAMP is an analogue of c-diAMP, the bacterial second messenger, which can be used to study ligand-receptor interactions.
Sp-2'-AHC-cAMPS is a PDE-stable analogue of cAMP used for immobilization as an affinity ligand or for coupling of labelling structures such as fluorophores.
c-di-2'-dAMP is an analogue of c-diAMP, the bacterial second messenger.
c[8-AET-G(2',5')pA(3',5')p] is an analogue of c[G(2',5')pA(3',5')p], the metazoan cyclic dinucleotide second messenger and STING activator, which is used as a l...
8-AET-c-diGMP is an analogue of c-diGMP, the bacterial second messenger, which can be used as a ligand for affinity chromatography or for coupling of labelling ...
6-AE-cAMP is often used as a ligand for affinity chromatography of cAMP and cGMP binding proteins.
8-Cl-cAMP is a selective cAMP analogue preferring protein kinase A type I. 8-Cl-cAMP has already been in several clinical trials to identify its inhibitory effe...
2'-O-MB-cGMP is a precursor of cGMP. cGMP is released after the metabolism of 2'-O-MB-cGMP by esterases. Compared to cGMP, it has more lipophilic and membrane-p...
Sp-8-PIP-cAMPS is a selective cAMP analogue with a preference for site B of protein kinase A type II.