|Molecular Formula||C11H12BrN5O6P · Na|
|Description||8-Br-2'-O-Me-cAMP is an activator of the exchange protein activated by cAMP (Epac) or cAMP-GEF without affecting protein kinase A.|
|Purity||≥ 98% by HPLC|
|Synonyms||8- Bromo- 2'- O- methyladenosine- 3', 5'- cyclic monophosphate, sodium salt|
c-(ApIp) is a hybrid cyclic dinucleotide consisting of a 5'-AMP and a 5'-IMP unit.
cGMP-AM is a precursor of cGMP, the second messenger. The polar active analogue is released after the metabolism of cGMP-AM by esterases.
8-CPT-cAMP is an activator of cAMP- and cGMP-dependent protein kinase and of Epac. It has an improved membrane permeability, phosphodiesterase stability and sel...
8-AET-c-diGMP-Agarose is the bacterial second messenger c-diGMP immobilized on agarose by an aminoethylthio spacer, which possibly can be used in affinity chrom...
8-OH-cAMP is a polar analogue of cAMP used for the study of extracellular cAMP receptors. When applied by patch clamp techniques, 8-OH-cAMP remains trapped insi...
Rp-8-AHA-cAMPS-Agarose is the metabolically stable protein kinase A inhibitor Rp-cAMPS immobilized on agarose by an aminohexylamino spacer, which can be used in...
2-Cl-ATP is an agonist of P2Y purinoceptor that inhibits soluble guanylate cyclase.
Rp-c-diGMPS is an analogue of c-diGMP, the bacterial second messenger, which can be used to study ligand-receptor interactions.
6-Bnz-8-PIP-cAMP is a stimulator of protein kinase A which has no activated effect on Epac. It can be active to the A site of cAK I in combination with site B I...
ara-cAMP is an analogue of cAMP, the second messenger. It is commonly used in receptor mapping studies and negative controls.
Rp-8-OH-cAMPS is a polar analogue of Rp-cAMPS, the protein kinase A inhibitor, used for the study of extracellular cAMP receptors. It inhibits mammalian cyclic ...
Sp-6-Phe-cAMPS is a selective and PDE-resistant stimulator of protein kinase A, which is used as an Epac-negative control.
8-AEA-cAMP is a ligand for affinity chromatography of cAMP and cGMP binding proteins. It can be modified with fluorophores and other markers.
Sp-8-AHA-cAMPS is a PDE-stable cAMP analogue used for immobilization as an affinity ligand or for coupling of labelling structures such as fluorophores. It is a...
2'-AEC-cGMP is a cGMP analogue used for immobilization as an affinity ligand or for coupling of labelling structures such as fluorophores.
Sp-8-Br-cGMPS is an activator of protein kinase G I α and protein kinase A. It has a resistant effect against cyclic nucleotide phosphodiesterases. Compared to ...