|Description||8-Aminoadenine is an adenine receptor agonist with Ki value of 0.0341 μM in HEK293 cells expressing an adenine binding site. It shows 190-fold increased potency at the human binding site over the rat adenine receptor. It inhibits adenine uptake and isoproterenol-stimulated cAMP accumulation. It may be used in the synthetic preparation of purine derivatives as competitive inhibitors of human erythrocyte membrane phosphatidylinositol 4-kinase. It is important in regulating myocardial oxygen consumption and coronary blood flow. It may take part in inflammation and immune responses.|
|Purity||≥98% by HPLC|
|Synonyms||9H-Purine-6,8-diamine; 1H-Purine-6,8-diamine (9CI); 6,8-Diamino-purine (8CI); NSC 21698|
A2B receptor antagonist 1
A potent antagonist of A2B adenosine receptor
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