|Description||7-Chlorokynurenic acid sodium salt is the sodium salt of 7-Chlorokynurenic acid, which is a water-soluble and very potent NMDA receptor antagonist acting at the strychnine-insensitive glycine binding site with IC50 value of 0.56 µM. It is also a potent competitive inhibitor of L-glutamate transport into synaptic vesicles. It is used in studies of schizophrenia and neuroprotection.|
|Purity||≥98% by HPLC|
|Synonyms||7-Chloro-4-hydroxyquinoline-2-carboxylic acid sodium salt|
DL-AP7, one of the first generation phosphono NMDA antagonists, could be used as an anticonvulsant.
Spaglumic acid is the most abundant peptide neurotransmitter in the mammalian CNS. Spaglumic acid is a weak activator of NMDA receptors and a highly selective a...
5,7-Dichlorokynurenic acid sodium salt
The sodium salt form of 5,7-Dichlorokynurenic acid, which is an effective antagonist at the glycine site of the NMDA receptor.
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CP 101606 is a potent and selective NR2B antagonist of N-Methyl-D-Aspartate (NMDA) glutamate receptors. It decreases pentylenetetrazol-induced seizures.
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