7-Chlorokynurenic acid sodium salt - CAS 1263094-00-3
Category: Inhibitor
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Molecular Formula:
C10H5ClNNaO3
Molecular Weight:
245.59
COA:
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Targets:
NMDA Receptor
Description:
7-Chlorokynurenic acid sodium salt is the sodium salt of 7-Chlorokynurenic acid, which is a water-soluble and very potent NMDA receptor antagonist acting at the strychnine-insensitive glycine binding site with IC50 value of 0.56 µM. It is also a potent competitive inhibitor of L-glutamate transport into synaptic vesicles. It is used in studies of schizophrenia and neuroprotection.
Purity:
≥98% by HPLC
Synonyms:
7-Chloro-4-hydroxyquinoline-2-carboxylic acid sodium salt
MSDS:
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InChIKey:
IFZYIORLNGNLEI-UHFFFAOYSA-M
InChI:
InChI=1S/C10H6ClNO3.Na/c11-5-1-2-6-7(3-5)12-8(10(14)15)4-9(6)13;/h1-4H,(H,12,13)(H,14,15);/q;+1/p-1
Canonical SMILES:
C1=CC2=C(C=C1Cl)NC(=CC2=O)C(=O)[O-].[Na+]
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Chemical Structure

CAS 1263094-00-3 7-Chlorokynurenic acid sodium salt

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