6H-​Pyrimido[4,​5-​b]​[1,​4]​benzodiazepin-​6-​one, 5,​11-​dihydro-​2-​[[2-​methoxy-​4-​(4-​methyl-​1-​piperazinyl)​phenyl]​amino]​-​5,​11-​dimethyl- - CAS 1234479-76-5
Catalog number: 1234479-76-5
Category: Inhibitor
Please be kindly noted products are not for therapeutic use. We do not sell to patients.
Molecular Formula:
C25H29N7O2
Molecular Weight:
459.54
COA:
Inquire
Targets:
ERK
Description:
An effective inhibitior of ERK5, could probably be used as an antitumor agent. IC50: 0.19μM(EC50 for cellular),of 0.087 μM(for enzymatic) and 0.087 μM(for LRRK2).
Purity:
98%
Appearance:
Powder
Synonyms:
CHEMBL1673039; SCHEMBL618262; BDBM50337127; ZINC66066276; CS-4938; HY-14403
Solubility:
10 mM in DMSO
Storage:
-20ºC Freeze
MSDS:
Inquire
Application:
An effective inhibitior of ERK5 and could probably be used as an antitumor agent.
Shelf Life:
As supplied, 2 years from the QC date provided on the Certificate of Analysis, when stored properly
Quantity:
Milligrams-Grams
InChIKey:
DDTPGANIPBKTNU-UHFFFAOYSA-N
InChI:
InChI=1S/C25H29N7O2/c1-29-11-13-32(14-12-29)17-9-10-19(22(15-17)34-4)27-25-26-16-21-23(28-25)30(2)20-8-6-5-7-18(20)24(33)31(21)3/h5-10,15-16H,11-14H2,1-4H3,(H,26,27,28)
Canonical SMILES:
CN1CCN(CC1)C2=CC(=C(C=C2)NC3=NC=C4C(=N3)N(C5=CC=CC=C5C(=O)N4C)C)OC
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Chemical Structure

CAS 1234479-76-5 6H-​Pyrimido[4,​5-​b]​[1,​4]​benzodiazepin-​6-​one, 5,​11-​dihydro-​2-​[[2-​methoxy-​4-​(4-​methyl-​1-​piperazinyl)​phenyl]​amino]​-​5,​11-​dimethyl-

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