|Molecular Formula||C10H16N5O13P3S (free acid)|
|Molecular Weight||539.24 (free acid)|
|Structure\Application||Thio | Nucleotides applied on Proteins/Enzymes|
|Description||6-Thio-GTP is a Vac-1-Rac signaling inhibitor that inhibits TNF-α-induced downstream signaling via JNK. It exhibits immunosuppressant effects.|
|Brife Description||Vac-1-Rac signaling inhibitor|
|Purity||≥ 95% by HPLC|
|Appearance||clear aqueous solution|
|Synonyms||6-Thio-guanosine-5'-triphosphate, Sodium salt|
|Application||6-Thio-GTP is a Vac-1-Rac signaling inhibitor.|
GTPαS can be accomplished by 50-thiophosphorylation of 7-methylguanosine in (MeO)3PO in the presence of 2,6-lutidine,12 followed by addition of tributylammonium...
AP3G (A cap) is a non-functional cap analog used in the synthesis of mRNA to estimate the level of cap-independent translation.
O-Propargyl-puromycin is an alkyne analog of puromycin.
5'-dIMPS is a potent, competitive inhibitor that regulates enzymes. It can interact with 2'-deoxyinosine-5'-monophosphate.
8-Bromo-cAMP is a cell-permeable cAMP analog that activates PKA. It inhibits cell growth, decreases proliferation, increases differentiation and induces apoptos...
GppNHp - Tetralithium salt
The tetrasodium salt form of GppNH2, one of the analogue of GTP, has been found to be probably useful in studies of modulating cell signals related to G protein...
6-Methylthio-inosine is an analog of inosine.
TNP-GDP is a trinitrophenol (TNP) substituted nucleotide analog.