|Molecular Formula||C10H17N6O12P3S (free acid)|
|Molecular Weight||538.25 (free acid)|
|Structure\Application||Phosphate modified Nucleotides | Thio|
|Purity||≥ 95% by HPLC|
|Appearance||clear aqueous solution|
|Synonyms||(6-Thio-GMPPNP); 6-Thio-guanosine-5'-[(β,γ)-imido]triphosphate, Sodium salt|
6-Methylthio-IMP is an antimetabolite that inhibits de novo purine synthesis. It exhibits an antitumor effect in vivo.
Rp-TTP-α-S is used for regulation of TTP-responsive receptors and determination of their stereospecificity. Compared to TTP, it is much more stable.
ddATP-α-S is used in mass spectrometric genotyping.
6-Fu-ATP-γ-S is an analogue used to specifically interact with modified receptor proteins (chemical genetics approach).
5'-CMPS is a potent, competitive inhibitor that regulates enzymes. It can interact with cytidine-5'-monophosphate.
Rp-GDP-α-S is a GDP binding proteins regulator with high stability, which is used for characterization of GDP-responsive receptors and determination of their st...
Sp-2'-O-Me-CTP-α-S is a CTP analogue that can be used for enzymatic introduction of phosphorothioate and modified 2'-OH groups into RNA.
6-Methylthio-inosine is an analog of inosine.