|Molecular Formula||C11H18N5O13P3S (free acid)|
|Molecular Weight||553.27 (free acid)|
|Structure\Application||Thio | Nucleotides applied on Proteins/Enzymes|
|Purity||≥ 95% by HPLC|
|Appearance||clear aqueous solution|
|Synonyms||6-Methylthioguanosine-5'-triphosphate, Sodium salt|
5'-UMPS is a potent, competitive inhibitor that regulates enzymes. It can interact with uridine-5'-monophosphate.
6-Mercaptopurine-riboside-5'-triphosphate is a metabolite of mercaptopurine, a thiopurine used as an immunosuppressive drug.
6-Methylthio-inosine is an analog of inosine.
6-Methylthio-IMP is an antimetabolite that inhibits de novo purine synthesis. It exhibits an antitumor effect in vivo.
Mant-GTPγS had lower affinities for Gαs and Gαi than GTPγS/GppNHp as assessed by inhibition of GTP hydrolysis of receptor-Gα fusion proteins. MANT-GTPγS was muc...