|Description||6-Iodonordihydrocapsaicin is a potent and competitive vanilloid TRPV1 (VR1) receptor antagonist with IC50 value of 10 nM. It inhibits capsaicin-induced [Ca2+]i increase in rat DRG neurons. It also inhibits guinea pig bladder and trachea contractions in vitro. It may induce luciferase gene expression.|
|Purity||≥99% by HPLC|
M344 is a potent HDAC inhibitor, which can also induced expression of the pro-apoptotic genes, Puma and Bax, together with the morphological features of apoptos...
CI 966 hydrochloride
The hydrochloride salt form of CI 966, which is an inhibitor of the GABA transporter and could be used as anticonvulsive as well as neuroprotective agent.
A novel synthetic antagonist for nucleic acid-sensing TLRs
Bisegliptin is an antidiabetic agent, but no detailed information has been published yet.
2-(p-Hydroxyanilino)-4-(p-chlorophenyl)thiazole (SK1-II) is a cell permeable, potent, and specific inhibitor of sphingosine kinase (IC50 = 0.5 μM). The compound...
A carcinogen as a a major metabolite of Nicotine in humans.
CGS 19755 is a potent and competitive NMDA receptor antagonist with anticonvulsant, anxiolytic, analgesic and neuroprotective activity.
Etretinate is a second-generation retinoid to treat severe psoriasis. It has been replaced by acitretin, a safer metabolite of etretinate.