|Description||6-Hydroxy-DL-DOPA is an allosteric inhibitor of RAD52 that suppresses RAD52 binding to single strand DNA binding domains (IC50 = 1.1 μM). 6-Hydroxy-DL-DOPA inhibits proliferation of BRCA-deficient cancer cells in vitro.|
|Brife Description||allosteric inhibitor of RAD52|
|Synonyms||2,5-Dihydroxy-DL-tyrosine; 6-Hydroxydopa; 6-Ohdopa; 2,5-Dihydroxytyrosine; 2,4,5-Trihydroxyphenylalanine|
Protein Kinase Inhibitors 1
Protein Kinase Inhibitors 1 is a HIPK2 inhibitor with IC50 of 74 nM and Kd of 9.5 nM.
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