|Molecular Formula||C22H26N6O7P · Na|
|Description||6-Bnz-8-PIP-cAMP is a stimulator of protein kinase A which has no activated effect on Epac. It can be active to the A site of cAK I in combination with site B I-selective analogues.|
|Purity||≥ 98% by HPLC|
8-Br-2'-O-Me-cGMP is an analogue of cGMP that does not activate both protein kinase G and Epac. It is often used as an inactive control versus 8-Br-cGMP.
5,6-DCl-cBIMP is a potent activator of protein kinase A, acting on both type I and II. It can be subsequently metabolized by cyclic nucleotide-dependent phospho...
8-Biotin-11-c-diAMP is an analogue of c-diAMP, the bacterial second messenger. It is a potential tracer in immunoassays and commonly used for affinity chromatog...
8-Br-cGMP is a stimulator of cGMP dependent protein kinases I α, I β & type II and cGMP-gated ion channels (cGMP agonist). Compared to cGMP, it has a superior s...
Sp-6-AE-cAMPS-Agarose is the protein kinase A activator Sp-cAMPS immobilized on agarose by an aminoethyl spacer, which can be used in affinity chromatography of...
2'-O-Me-cAMP is a polar analogue of cAMP that cannot activate protein kinase A.
8-Cl-cAMP is a selective cAMP analogue preferring protein kinase A type I. 8-Cl-cAMP has already been in several clinical trials to identify its inhibitory effe...
6-AE-cAMP is often used as a ligand for affinity chromatography of cAMP and cGMP binding proteins.
4-MB-cCMP is an analogue of cCMP, the putative second messenger nucleotide and the main cellular metabolite of DB-cCMP. 4-MB-cCMP exhibits a partial activity of...
Sp-6-Phe-cAMPS is a selective and PDE-resistant stimulator of protein kinase A, which is used as an Epac-negative control.
8-Biotin-11-c-diGMP is an analogue of c-diGMP, the bacterial second messenger. It is a potential tracer in immunoassays and commonly used for affinity chromatog...
2'-AHC-c-diGMP-Agarose is the bacterial second messenger c-diGMP immobilized on agarose by an aminohexylcarbamoyl spacer which can be used in affinity chromatog...
c[G(2',5')pA(3',5')p] / 2'3'-cGAMP
c[G(2',5')pA(3',5')p] was considered to be the metazoan second messenger which is produced by cGAMP synthase (cGAS), the mammalian intrinsic immune DNA sensor. ...
8-AET-c-diGMP-Agarose is the bacterial second messenger c-diGMP immobilized on agarose by an aminoethylthio spacer, which possibly can be used in affinity chrom...
2'-AEC-cGMP is a cGMP analogue used for immobilization as an affinity ligand or for coupling of labelling structures such as fluorophores.
Sp-8-AEA-cAMPS is a phosphodiesterase-resistant ligand for affinity chromatography of cAMP and cGMP binding proteins. It is often modified with fluorophores and...
Sp-8-Br-2'-O-Me-cAMPS is a anti-hydrolytic form of 8-Br-2'-O-Me-cAMP, a specific membrane-permeant stimulator of the exchange protein activated by cAMP (Epac) o...