6-alpha-methyl prednisolone aceponate - CAS 86401-95-8
Catalog number: B1742-078560
Molecular Formula:
C27H36O7
Molecular Weight:
472.58
COA:
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Description:
6-alpha-methyl prednisolone aceponate is a derivative of prednisolone. It can be used in the treatment of seborrhoeic dermatitis.
Ordering Information
Catalog Number Size Price Stock Quantity
B1742-078560 100 mg $298 In stock
B1742-078560 250 mg $598 In stock
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Purity:
>95%
Appearance:
White to Off-white Solid
Synonyms:
6α-Methyl Prednisolone Aceponate; (6α,11β)-21-(Acetyloxy)-11-hydroxy-6-methyl-17-(1-oxopropoxy)pregna-1,4-diene-3,20-dione; Advantan; ZK 91588
MSDS:
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Melting Point:
105-108°C
InChIKey:
DALKLAYLIPSCQL-YPYQNWSCSA-N
InChI:
InChI=1S/C27H36O7/c1-6-23(32)34-27(22(31)14-33-16(3)28)10-8-19-18-11-15(2)20-12-17(29)7-9-25(20,4)24(18)21(30)13-26(19,27)5/h7,9,12,15,18-19,21,24,30H,6,8,10-11,13-14H2,1-5H3/t15-,18-,19-,21-,24+,25-,26-,27-/m0/s1
Canonical SMILES:
CCC(=O)OC1(CCC2C1(CC(C3C2CC(C4=CC(=O)C=CC34C)C)O)C)C(=O)COC(=O)C
1.Fast itch relief in an experimental model for methylprednisolone aceponate topical corticosteroid activity, based on allergic contact eczema to nickel sulphate.
Curto L1, Carnero L, López-Aventin D, Traveria G, Roura G, Giménez-Arnau AM. J Eur Acad Dermatol Venereol. 2014 Oct;28(10):1356-62. doi: 10.1111/jdv.12292. Epub 2013 Nov 4.
BACKGROUND: Topical corticosteroids (TC) consistently show effectiveness against itch, a paradigmatic symptom, in various eczemas. Rapid itch relief is a therapeutic goal. The early response of itch to TC has not been adequately studied.
2.Scabies acquired in Chinese massage centers.
Veraldi S1, Cuka E, Francia C, Persico MC. G Ital Dermatol Venereol. 2014 Oct;149(5):627-8.
3.[Multiple larva migrans on the foot of a traveller].
Lobato-Berezo A1, Vargas-Laguna ME2, Fernández-Cogolludo E2, Gallego-Valdés MÁ2. Med Clin (Barc). 2015 Jun 22;144(12):576. doi: 10.1016/j.medcli.2014.12.003. Epub 2015 Jan 28.
4.[Exudative onycholysis and acute bacterial paronychia related to BIBF-1120 and paclitaxel: response to topical therapy].
Freites-Martínez A, Martinez-Sánchez D, de Pablo NP, Calderón-Komaromy A, Córdoba S, Burbujo J. Invest Clin. 2014 Mar;55(1):55-60.
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Chemical Structure

CAS 86401-95-8 6-alpha-methyl prednisolone aceponate

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