|Description||5HT6-ligand-1 is a potent 5-HT6 receptor ligand (Ki= 1.43 nM).|
|Synonyms||1H-Indole, 1-[(2-bromophenyl)sulfonyl]-4-[(4-methyl-1-piperazinyl)methyl]-; 1-(2-bromophenyl)sulfonyl-4-[(4-methylpiperazin-1-yl)methyl]indole|
|Storage||Store in a cool and dry place (or refer to the Certificate of Analysis).|
|Boiling Point||587.1±60.0 ℃ at 760 Torr|
Elzasonan citrate is a selective 5-hydroxytryptamine 1B receptor antagonist for treat patients with major depressive disorder and obsessive compulsive disorder.
Ondansetron is a serotonin 5-HT3 receptor antagonist used mainly as an antiemetic.
WAY-100635 is an achiral analogue of WAY-100135 which is significantly more potent and selective than the latter compound and which displays unequivocal 5-HTIA ...
LY 344864 hydrochloride
LY 344864 hydrochloride is a 5-HT1F receptor agonist with EC50 value of 3 nM.
LY 215840 is a potent antagonist of both Serotonin 2A receptor and Serotonin 7 receptor. It can reduce stimulatory effect of serotonin on aldosterone secretion ...
LY 125180 is a serotonin antagonist.It can effect on serotonin uptake and serotonin synthesis in rat brain in vitro and in vivo.
AMI-193 has been found to be a selective 5-HT antagonist and could be also used as a starting reagent in some pharmaceutical synthesis.
GMC 1-165 is an analogue of clozapine with 5-HT2A/2C and hM1 receptor affinities.
RS 127445 hydrochloride
RS-127445 is a selective, high affinity, orally bioavailable serotonin 5-HT2B receptor antagonist (pKi = 9.5), which displays 1000-fold selectivity for 5-HT2B w...
The salt form of (R)-6-hydroxybuspirone, which is an active metabolite of Buspirone. It is a 5-HT1A partial agonist with higher affinity for 5HT1A receptor comp...
GMC 1-116 is a metabolite of clozapine with weak 5-HT2 affinity and high M1 affinity (IC50 = 27 nM).
MK 212 hydrochloride
MK 212 hydrochloride is a 5-HT2C receptor agonist.
PNU 96415E, chemically unrelated to clozapine, exhibits high affinity for dopamine D4 and serotonergic 5-HT2A receptors and relatively weak affinity at D2 recep...
Iloperidone displays high affinity (Ki < 10 nM) for norepinephrine alpha(1)-adrenoceptors, dopamine D(3) and serotonin 5-HT(2A) receptors.
Alprenolol hydrochloride is the hydrochloride salt of alprenolol, which is a non-selective 5-HT1A receptor antagonist and beta blocker. It is used in the treatm...
N-Methylquipazine dimaleate, a tertiary amine analog of quipazine, is a 5-HT3 agonist, which has almost the same affinity for 5-HT3 sites as quipazine but unlik...
RO 04-6790 hydrochloride
RO 04-6790 hydrochloride is a potent and selective serotonin 5-HT6 receptor antagonist.
BMY 14802 hydrochloride
BMY 14802 hydrochloride is a potent sigma receptor antagonist (IC50 = 112 nM) with weak affinity for 5-HT1A and α1 receptors. BMY 14802 is potentially used as a...
WAY 161503 hydrochloride
WAY 161503 hydrochloride is a potent and selective 5-HT2C receptor agonist (Ki = 4 nM; EC50 = 12 nM).
Ritanserin is a potent and long-acting 5-HT2 receptor antagonist (Ki = 0.39 nM) with high selectivity for 5-HT2A over 5-HT1 receptors (IC50s = 0.9 nM and >1000 ...