5-Iodotubercidin - CAS 24386-93-4
Catalog number:
24386-93-4
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C11H13IN4O4
Molecular Weight:
392.15
COA:
Inquire
Targets:
Adenosine Kinase
Description:
5-Iodotubercidin, an adenosine derivative, is a potent adenosine kinase inhibitor (IC50 = 26 nM). And 5-Iodotubercidin also inhibits mitogen-activated protein kinase (ERK2) (Ki = 525 nM), nucleoside transporter inhibitor (IC50 values are < 25 nM, 7 μM and
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Purity:
>90 %
Appearance:
Tan Solid
Synonyms:
(2R,3R,4S,5R)-2-(4-amino-5-iodopyrrolo[2,3-d]pyrimidin-7-yl)-5-(hydroxymethyl)oxolane-3,4-diol 5'-iodotubericidin 5-iodotubercidin
Solubility:
Soluble to ≥ 49 mg/mL in DMSO
Storage:
Store in a cool and dry place and at 0 - 4℃ for short term (days to weeks) or -113℃ for long term (months to years).
MSDS:
Inquire
Application:
An analogue of the antibiotic tubercidin, a pyrrolo[2,3-d]pyrimidine nucleoside antibiotic. A potent inhibitor of adenosine kinase from rat or guinea pig brain. Inhibits uptake of 3H-adenosine into brain slices.
Shelf Life:
2 years
Boiling Point:
701.5±60.0 °C | Condition: Press: 760 Torr
Melting Point:
215 °C ( Solv: methanol)
Density:
2.49 g/cm3
InChIKey:
WHSIXKUPQCKWBY-IOSLPCCCSA-N
InChI:
1S/C11H13IN4O4/c12-4-1-16(10-6(4)9(13)14-3-15-10)11-8(19)7(18)5(2-17)20-11/h1,3,5,7-8,11,17-19H,2H2,(H2,13,14,15)/t5-,7-,8-,11-/m1/s1
Canonical SMILES:
C1=C(C2=C(N1C3C(C(C(O3)CO)O)O)N=CN=C2N)I
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CAS 24386-93-4 5-Iodotubercidin

5-Iodotubercidin
(CAS: 24386-93-4)

5-Iodotubercidin, an adenosine derivative, is a potent adenosine kinase inhibitor (IC50 = 26 nM). And 5-Iodotubercidin also inhibits mitogen-activated protein k...

Chemical Structure

CAS 24386-93-4 5-Iodotubercidin

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