|Description||5-Iodo-A-85380 dihydrochloride is the dihydrochloride salt of 5-Iodo-A-85380, which is a highly potent and subtype-selective agonist for α4β2 and α6β2 nicotinic acetylcholine receptors. It activates α-CTx-MII-sensitive and -insensitive components of [3H]dopamine release from rat striatal synaptosomes.|
|Purity||≥99% by HPLC|
3-Bromocytisine has been found to be an α4β4, α4β2 and α7 nACh receptor agonist.
Pancuronium results in open channel block of embryonic-type nicotinic acetylcholine receptor channels after coapplication of blocker and acetylcholine。
Cytisine is a nicotinic acetylcholine receptor (nAChR) agonist. It has been used medically to help with smoking cessation.
The hydrochloride salt form of Desformylflustrabromine, which has been found to be a positive allosteric modulator of α4β2 nicotinic acetylcholine receptors.
Chlorisondamine diiodide is an exceptionally long-lasting and irreversible nicotinic acetylcholine receptor antagonist with IC50 value of 1.6 mM. It blocks cent...
Adiphenine HCl is a nicotinic receptor inhibitor with IC50 of 15 μM, used as an antispasmodic drug.
UB 165 fumarate
UB 165 fumarate is a full agonist at α3β2- and a weak partial agonist at α4β2- containing nAChRs (Ki = 0.27, 20 (IC50), 2790 and 990 nM for α4β2, α3, α7 and α1β...
AZD 0328 is a potent α7 NNR/5HT3 receptor agonist. AZD0328 led to a significant increase in cortical dopamine release in awake rodents and improved both conditi...