5-hydroxypyrazine-2-carboxylic acid - CAS 34604-60-9
Catalog number: 34604-60-9
Category: Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C5H4N2O3
Molecular Weight:
140.1
COA:
Inquire
Targets:
Antibacterial
Description:
A versatile building block for the synthesis of new antituberculous agents. A metabolite of Pyrazinamide.
Publictions citing BOC Sciences Products
  • >> More
Purity:
>98%
Synonyms:
4,5-Dihydro-5-oxopyrazinecarboxylic Acid; 5-Hydroxypyrazinecarboxylic Acid; 5-Hydroxypyrazinoic acid; 5-Oxo-4,5-dihydropyrazine-2-carboxylic Acid
MSDS:
Inquire
1.Biowaiver Monographs for Immediate Release Solid Oral Dosage Forms: Pyrazinamide
C. BECKER, J.B. DRESSMAN. JOURNAL OF PHARMACEUTICAL SCIENCES, VOL. 97, NO. 9, SEPTEMBER 2008
The purpose and scope of this series of monographs have been previously discussed. Summarized in few words, the aim is to evaluate all pertinent data available from literature sources for a given API to assess the risks associated with a biowaiver. For these purposes, risk is defined as the probability of an incorrect biowaiver decision as well as the consequences of the decision in terms of public health and individual patient risks. On the basis of these considerations, a recommendation can be made as to whether a biowaiver approval is advisable or not. This systematic approach to recommend or advise against a biowaiver decisions is referred to in the recently published World Health Organization (WHO) Guideline. It is pointed out that these monographs do not simply apply this WHO Guideline, nor the FDA and/or EMEA Guidance, but also want to serve as a critical validation of these regulatory documents. Biowaiver monographs have already been published for acetaminophen (INN: paracetamol), amitriptyline, atenolol, chloroquine, cimetidine, ethambutol, ibuprofen, isoniazid, prednisolone, prednisone, propranolol, ranitidine, and verapamil. They are also available online at the website of the International Pharmaceutical Federation FIP.
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

Related Antibacterial Products


CAS 85721-33-1 Ciprofloxacin

Ciprofloxacin
(CAS: 85721-33-1)

Ciprofloxacin is a fluoroquinolone antibiotic, shows broad and potent antibacterial activity, with MIC90 of 0.024-6 μM.

FR-193879
(CAS: 194928-82-0)

FR-193879, a cephem derivative, is an efficacious anti-Helicobacter pylori cephalosporin.

CAS 121123-17-9 Cefprozil monohydrate

Cefprozil monohydrate
(CAS: 121123-17-9)

Cefprozil hydrate (Cefzil) is a second-generation cephalosporin type antibiotic. Cefprozil hydrate (Cefzil) can be used to treat bronchitis, ear infections, ski...

CAS 50972-17-3 Bacampicillin

Bacampicillin
(CAS: 50972-17-3)

Bacampicillin may increase the anticoagulant activities of Acenocoumarol as a prodrug of ampicillin.

CAS 843663-66-1 Bedaquiline

Bedaquiline
(CAS: 843663-66-1)

TMC207 is a first-in-class diarylquinoline compound with a novel mechanism of action, the inhibition of bacterial ATP synthase, and potent activity against drug...

CAS 105956-97-6 Clinafloxacin

Clinafloxacin
(CAS: 105956-97-6)

Clinafloxacin is a broad-spectrum antibiotic of the quinolone carboxylic acid category currently in development for intravenous and oral therapy of serious infe...

CAS 84294-96-2 Enoxacin hydrate

Enoxacin hydrate
(CAS: 84294-96-2)

Enoxacin hydrate is a synthetic antibiotic belonging to quinolone carboxylic acid compound. It is bactericidal and has a postantibiotischen effect. It is a broa...

CAS 186826-86-8 Moxifloxacin HCl

Moxifloxacin HCl
(CAS: 186826-86-8)

Moxifloxacin exerts its effects by trapping a DNA drug enzyme complex and specifically inhibiting ATP-dependent enzymes topoisomerase II (DNA gyrase) and topoisom...

CAS 74-55-5 Ethambutol

Ethambutol
(CAS: 74-55-5)

Ethambutol is a bacteriostatic antimycobacterial agent, which obstructs the formation of cell wall by inhibiting arabinosyl transferases. lt directly affects tw...

Ribocil-C
(CAS: 1825355-56-3)

Ribocil-C is a more active analog of ribocil. Ribocil is a potent and highly selective synthetic mimic of FMN and inhibit bacterial growth both in vitro and in ...

CAS 13614-98-7 Minocycline Hydrochloride

Minocycline Hydrochloride
(CAS: 13614-98-7)

Minocycline Hydrochlorideis the most lipid soluble and most active tetracycline antibiotic, binds to the 30S ribosomal subunit, preventing the binding of tRNA t...

CAS 165800-03-3 Linezolid

Linezolid
(CAS: 165800-03-3)

Linezolid inhibits initiation complex formation with either the 30S or the 70S ribosomal subunits from Escherichia coli.

CAS 80214-83-1 Roxithromycin

Roxithromycin
(CAS: 80214-83-1)

Roxithromycin is a semi-synthetic macrolide antibiotic that inhibits bacterial cell growth and replication. It is used to treat respiratory tract, urinary and s...

CAS 56-75-7 Chloramphenicol

Chloramphenicol
(CAS: 56-75-7)

Chloramphenicol is an antibiotic useful for the treatment of a number of bacterial infections.

Antibiotic-202
(CAS: 1616113-45-1)

Antibiotic-202 has antibacterial property.

CAS 15318-45-3 Thiamphenicol

Thiamphenicol
(CAS: 15318-45-3)

Thiamphenicol is an antimicrobial antibiotic and a methyl-sulfonyl analogue of chloramphenicol.

CAS 23325-78-2 Cephalexin monohydrate

Cephalexin monohydrate
(CAS: 23325-78-2)

A semisynthetic cephalorsporin antibiotic.

CAS 56796-39-5 Cefmetazole Sodium

Cefmetazole Sodium
(CAS: 56796-39-5)

Cefmetazole Sodium , contains an N-methylthiotetrazole side chain, is a semisynthetic cephamycin antibiotic with a broad spectrum of activity as a second-genera...

CAS 64-72-2 Chlortetracycline HCl

Chlortetracycline HCl
(CAS: 64-72-2)

Chlortetracycline HCl is the first identified tetracycline antibiotic.

Vaborbactam
(CAS: 1360457-46-0)

Vaborbactam is a selective beta-lactamase inhibitor under the development of Rempex Pharmaceuticals. Vaborbactam is a broad-spectrum inhibitor, especially resto...

Chemical Structure

CAS 34604-60-9 5-hydroxypyrazine-2-carboxylic acid

Quick Inquiry

Verification code

Featured Items