|Molecular Formula||C28 H18 N2 O6|
|Description||4E1RCat is a dual inhibitor of eIF4E:eIF4G and eIF4E:4E-BP1 interaction, and inhibits the binding of eIF4G to eIF4E with IC50 of 3.2 μM.|
Pixantrone is a synthetic, noncardiotoxic aza-anthracenedione analogue with potential antineoplastic activity. Pixantrone intercalates into DNA and induces topo...
Acetohexamide, a sulfonylurea derivative, is a first-generation sulfonylurea medication used to treat diabetes mellitus type 2, particularly in people whose dia...
Ibandronate (< 100 μM) inhibits growth of both prostate cancer cell lines (LNCaP and PC-3) in a dose dependent manner.
OKT3-induced PBMC proliferation was inhibited by octahydrocurcumin with IC50 of 82 uM. The investigated substances with the strongest effect on radical scavengi...
SBC-115076 is a potent extracellular proprotein convertase subtilisin kexin type 9 (PCSK9) antagonist. .
O-Desmethyl Mebeverine Acid
O-Desmethyl Mebeverine Acid is a metabolite of Mebeverine, which is an antispasmodic.
OTS-514, a quinolone derivative, is an effective TOPK inhibitor and has been found to have potential effect against Renal cancer. It is still under preclinical ...
Azoramide is a modulator of the unfolded protein response with antidiabetic activity. It is a dual-function endoplasmic reticulum (ER) modulator in vitro. It im...
Binfloxacin, a bio-active chemical compound, has antibiotic effect.
PK14105, a isoquinoline derivative, could bind to peripheral-type benzodiazepine sites so that it might be a potential radioligand to locate areas of neuronal d...
ABT 38396 is a synthetic bio-active chemical.
Sulisobenzoneis a UV filter which protects the skin from damage by UVB and short-wave UVA ultraviolet light
CGP 55802A has been found to be a photoaffinity ligand that could be used to label NMDA receptor and have high selectivity to glutamate recognition site.
FG8119 is a novel benzodiazepine agonist.
Sobetirome selectively binds to and activates TRbeta over TRalpha and this receptor selectivity led to the hypothesis that sobetirome would lower cholesterol th...
Albiflorin is a major constituent presents in peony root, which possesses therapeutic potential for neurodegenerative diseases.
Mitiglinide is a succinic acid derivative with hypoglycemic activity. It belongs to the meglitinide class of blood glucose-lowering drugs. It is a drug for the ...
Dronedarone is a Class III antiarrhythmic and a multi-channel blocker for atrial fibrillation. It blocks potassium, sodium, and calcium channels and also exhibi...
Schisandrin has various therapeutic effects on a range of medical conditions such as anti-asthmatic, anti-cancer, and anti-inflammatory effects.
Remeglurant is a selective Metabotropic glutamate receptor 5 antagonist originated by Merz Pharmaceuticals. Phase-I for Drug-induced dyskinesia in USA was on-go...