|Description||4-Methylpyrazole is a competitive inhibitor of alcohol dehydrogenase, which catalyzes metabolism of ethylene glycol and methanol to toxic metabolites. It is used as an antidote for ethylene glycol or methanol poisoning. It may be used alone or in combination with hemodialysis. It can prevent the formation of toxic alcohol metabolites that generate metabolic acidosis at 10 µM in monkeys. It also inhibits CYP2E1 activity. It is on the World Health Organization's List of Essential Medicines, the most important medications needed in a basic health system.|
|Appearance||Clear colorless to yellow liquid after melting|
|Solubility||H2O: ＞ 146 mg/mL|
|Application||4-Methylpyrazole is used as an antidote for ethylene glycol or methanol poisoning. It also inhibits CYP2E1 activity.|
|Quality Standard||In-house standard|
|Shelf Life||2 month in rt, long time|
|Quantity||Kilogram to ton|
|Boiling Point||206 °C|
|Melting Point||15.5-18.5 °C|
|Density||1.062±0.06 g/cm3 | Condition: Temp: 20 °C Press: 760 Torr|
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