|Molecular Formula||C13H17N3O8P · Na|
|Description||4-MB-cCMP is an analogue of cCMP, the putative second messenger nucleotide and the main cellular metabolite of DB-cCMP. 4-MB-cCMP exhibits a partial activity of PKG Iα in vitro and in vivo, and a full activity of PKA RIα and PKA RIIα in vitro.|
|Purity||≥ 97% by HPLC|
|Synonyms||N4- Monobutyrylcytidine- 3', 5'- cyclic monophosphate, sodium salt|
Rp-cAMPS, sodium salt
Rp-cAMPS is a competitive inhibitor of protein kinase A type I and II (cAMP antagonist), which has a higher affinity for type II of protein kinase A. It exhibit...
2'-AHC-cAMP is an analogue of cAMP used for immobilization as an affinity ligand or for coupling of labelling structures such as fluorophores.
2'-AEC-cAMP is a ligand for affinity chromatography of cAMP and cGMP binding proteins. It is often modified with fluorophores and other markers.
6-AH-cAMP-Agarose is the second messenger cAMP immobilized on agarose by an aminohexyl spacer which can be used in affinity chromatography of cyclic nucleotide-...
8-pCPT-2'-O-Me-cAMP-AM is a precursor of 8-pCPT-2'-O-Me-cAMP, the specific Epac agonist. 8-pCPT-2'-O-Me-cAMP is released after the metabolism of 8-pCPT-2'-O-Me-...
Rp-cCMPS is a PDE-resistant cCMP, the potential second messenger, which inhibits cCMP-binding proteins.
8-ADOA-cAMP is a selective and hydrophilic cAMP analogue, which is used as a ligand in affinity chromatography and can be modified with fluorophores.
8-Br-2'-O-Me-cAMP is an activator of the exchange protein activated by cAMP (Epac) or cAMP-GEF without affecting protein kinase A.
c[G(2',5')p-2'-Biotin-16-A(3',5')p] is an analogue of c[G(2',5')pA(3',5')p], the metazoan cyclic dinucleotide second messenger and STING activator. It is a pote...
4-N3-PET-8-Br-cGMP is an analogue used for photoaffinity labelling of cGMP-responsive receptors, and an isozyme-selective activator of cGMP-dependent protein ki...
c-(Ap-8-AET-Gp)-Agarose is the bacterial second messenger c-(ApGp) immobilized on agarose by an aminoethylthio spacer, which possibly can be used in affinity ch...
c[G(2',5')p-2'-dA(3',5')p] is a 2'-deoxy analogue of c[G(2',5')pA(3',5')p], the metazoan cyclic dinucleotide second messenger and STING stimulator, which can be...
c-hexaAMP is a novel bacterial second messengers involved in the Type III CRISPR-Cas-associated detection and degradation of invasive genetic elements in many p...
8-Cl-cAMP is a selective cAMP analogue preferring protein kinase A type I. 8-Cl-cAMP has already been in several clinical trials to identify its inhibitory effe...
c[A(2',5')pG(2',5')p] / 2'2'-cGAMP
c[A(2',5')pG(2',5')p] is a cyclic dinucleotide analogue of c[G(2',5')pA(3',5')p], the metazoan second messenger and STING activator. It can bind the signalling ...
Sp-8-CPT-cAMPS is a selective activator of protein kinase A (cAMP agonist). It effects against mammalian cyclic nucleotide-dependent phosphodiesterases.
Sp-8-pCPT-2'-O-Me-cAMPS is an activator of the exchange protein activated by cAMP (Epac) or cAMP-GEF, which is inactive for protein kinase A. It is much more li...