4-(4-Hydroxyphenyl)-2-butanone - CAS 5471-51-2
Catalog number: 5471-51-2
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C10H12O2
COA:
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Chemical Family:
Phenols
Purity:
>98%
Appearance:
Powder
Synonyms:
Raspberry ketone natural; 2-(4-Hydroxyphenyl)ethyl methyl ketone; 4-Hydroxybenzylacetone;
MSDS:
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Quality Standard:
Enterprise Standard
Quantity:
Grams-Kilos
1.Eight weeks of supplementation with a multi-ingredient weight loss product enhances body composition, reduces hip and waist girth, and increases energy levels in overweight men and women.
Lopez HL;Ziegenfuss TN;Hofheins JE;Habowski SM;Arent SM;Weir JP;Ferrando AA J Int Soc Sports Nutr. 2013 Apr 19;10(1):22. doi: 10.1186/1550-2783-10-22.
BACKGROUND: ;Numerous natural products are marketed and sold claiming to decrease body weight and fat, but few undergo finished product-specific research demonstrating their safety and efficacy.;OBJECTIVE: ;To determine the safety and efficacy of a multi-ingredient supplement containing primarily raspberry ketone, caffeine, capsaicin, garlic, ginger and Citrus aurantium (Prograde Metabolism™ [METABO]) as an adjunct to an eight-week weight loss program.;METHODS: ;Using a randomized, placebo-controlled, double-blind design, 70 obese but otherwise healthy subjects were randomly assigned to METABO or a placebo and underwent 8 weeks of daily supplementation, a calorie restricted diet, and exercise training. Subjects were tested for changes in body composition, serum adipocytokines (adiponectin, resistin, leptin, TNF-α, IL-6) and markers of health including heart rate and blood pressure.;RESULTS: ;Of the 45 subjects who completed the study, significant differences were observed in: body weight (METABO -2.0% vs. placebo -0.5%, P < 0.01), fat mass (METABO -7.8 vs. placebo -2.8%, P < 0.001), lean mass (METABO +3.4% vs. placebo +0.8%, P < 0.03), waist girth (METABO -2.0% vs. placebo -0.2%, P < 0.
2.Sexual selection in true fruit flies (Diptera: Tephritidae): transcriptome and experimental evidences for phytochemicals increasing male competitive ability.
Kumaran N;Prentis PJ;Mangalam KP;Schutze MK;Clarke AR Mol Ecol. 2014 Sep;23(18):4645-57. doi: 10.1111/mec.12880. Epub 2014 Sep 6.
In male tephritid fruit flies of the genus Bactrocera, feeding on secondary plant compounds (sensu lato male lures = methyl eugenol, raspberry ketone and zingerone) increases male mating success. Ingested male lures alter the male pheromonal blend, normally making it more attractive to females and this is considered the primary mechanism for the enhanced mating success. However, the male lures raspberry ketone and zingerone are known, across a diverse range of other organisms, to be involved in increasing energy metabolism. If this also occurs in Bactrocera, then this may represent an additional benefit to males as courtship is metabolically expensive and lure feeding may increase a fly's short-term energy. We tested this hypothesis by performing comparative RNA-seq analysis between zingerone-fed and unfed males of Bactrocera tryoni. We also carried out behavioural assays with zingerone- and cuelure-fed males to test whether they became more active. RNA-seq analysis revealed, in zingerone-fed flies, up-regulation of 3183 genes with homologues transcripts to those known to regulate intermale aggression, pheromone synthesis, mating and accessory gland proteins, along with significant enrichment of several energy metabolic pathways and gene ontology terms.
3.[Studies on non-anthraquinones in Rheum officinale Baill].
Li JL;Wang AQ;Wu ZZ Zhongguo Zhong Yao Za Zhi. 2000 Oct;25(10):612-4.
OBJECTIVE: ;To investigate the non-anthraquinones from the root and rootstock of Rheum officinale.;METHOD: ;The chemical constituents were obtained from the 85% alcohol extract of the radix and rhizoma of R. officinale by column chromatography and identified by spectroscopic analysis.;RESULT: ;Ten non-anthraquinones were obtained, of which eight were identified by spectroscopic analysis as rheosmine, daucosterol, d-catechin, 6-cinnamoylisolindleyin, (-)-epicatechin-3-O-gallate, resveratrol-4'-O-beta-D-(6"-O-galloyl)-glucopyranoside, gallic acid, D-sorbitol.;CONCLUSION: ;Compounds rheosmine and D-sorbitol were obtained from the genus Rheum for the first time.
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CAS 5471-51-2 4-(4-Hydroxyphenyl)-2-butanone

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