3-Methylsalicylic acid - CAS 83-40-9
Catalog number: 83-40-9
Category: Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C8H8O3
Molecular Weight:
152.15
COA:
Inquire
Targets:
Others
Description:
3-Methylsalicylic acid has marked fibrinolytic activity in human plasma by activating its fibrinolytic system. It is a salicylic acid derivative compound, which toxicity is similar to salicylic acid. It is used in manufacturing of dyes.
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Purity:
99%
Appearance:
White to off-white or pale pink powder
Synonyms:
AKOS BBS-00003735;2-Anisic acid;FEMA 3943;2,3-Cresotic acid;2,3-Cresotinic acid;2-Hydroxy-3-methylbenzoic acid;Hydroxytoluic acid;O-Cresotinic acid;2-hydroxy-m-toluic acid;o-Kresotinic Acid
Solubility:
DMSO: ≥ 1.5 mg/mL
Storage:
-20°C Freezer
MSDS:
Inquire
Application:
3-Methylsalicylic acid has marked fibrinolytic activity in human plasma by activating its fibrinolytic system. It is used in manufacturing of dyes.
Quality Standard:
In-house standard
Shelf Life:
2 month in rt, long time
Quantity:
Kilogram to ton
Boiling Point:
293.2±28.0 °C | Condition: Press: 760 Torr
Melting Point:
165.5 °C
Density:
1.304±0.06 g/cm3 | Condition: Temp: 20 °C Press: 760 Torr
InChIKey:
WHSXTWFYRGOBGO-UHFFFAOYSA-N
InChI:
InChI=1S/C8H8O3/c1-5-3-2-4-6(7(5)9)8(10)11/h2-4,9H,1H3,(H,10,11)
Canonical SMILES:
CC1=CC=CC(=C1O)C(=O)O
1.Bacterial metabolism of para- and meta-xylene: oxidation of a methyl substituent.
Davey JF, Gibson DT. J Bacteriol. 1974 Sep;119(3):923-9.
Pseudomonas Pxy was isolated on p-xylene as sole source of carbon and energy. Substrates that supported growth were toluene, p-methylbenzyl alcohol, p-tolualdehyde, p-toluic acid, and the analogous m-methyl derivatives, including m-xylene. Cell extracts prepared from Pseudomonas Pxy after growth with either p-xylene or m-xylene oxidized the p- and m-isomers of tolualdehyde as well as p-methylbenzyl alcohol. The same cell extracts also catalyzed a "meta" fission of both 3- and 4-methylcatechol. Treatment of Pseudomonas Pxy with N-methyl-N'-nitro-N-nitrosoguanidine led to the isolation of two mutant strains. Pseudomonas Pxy-40, when grown on succinate in the presence of p-xylene, accumulated p-toluic acid in the culture medium. Under the same conditions Pseudomonas Pxy-82 accumulated p-toluic acid and also 4-methylcatechol. When Pseudomonas Pxy-82 was grown on succinate in the presence of m-xylene, 3-methylcatechol and 3-methylsalicylic acid were excreted into the culture medium.
2.The complete assignment of the 13C NMR spectra of lasalocid and the sodium salt-complex of the antibiotic.
Seto H, Westley JW, Pitcher RG. J Antibiot (Tokyo). 1978 Apr;31(4):289-93.
All thirty-four signals observed in the 13C nmr of both the free acid form (Ia) and sodium salt (Ib) of the polyether antibiotic lasalocid have been assigned. This was achieved using model compounds such as 3-methylsalicylic acid, the retroaldol ketones from both lasalocid and lysocellin and a gamma-lactone from a third polyether, salinomycin. The last assignments to be made were accomplished using biosynthetically enriched samples of the antibiotic.
3.Synthesis and characterisation of tungsten(VI) oxo-salicylate complexes for use in the chemical vapour deposition of self-cleaning films.
Cross WB1, Parkin IP, White AJ, Williams DJ. Dalton Trans. 2005 Apr 7;(7):1287-93. Epub 2005 Mar 3.
Tungsten(VI) oxo-salicylate complexes were prepared in moderate yield (47 to 63%) by the reactions of WOCl4 and two equivalents of either 3-methylsalicylic acid (MesaliH2) or 3,5-di-isopropylsalicylic acid (di-i-PrsaliH2). Performing the reaction in refluxing toluene afforded the two analogous ditungsten complexes 1, [{WO(Mesali)(MesaliH)}2(mu-O)], and 2, [{WO(di-i-Prsali)(di-i-PrsaliH)}2(mu-O)], however in refluxing hexane the mononuclear tungsten complex , [WO(di-i-Prsali)(di-i-PrsaliH)Cl], was isolated. The single crystal X-ray study of revealed a pseudo-octahedral geometry around the tungsten centres. Aerosol assisted chemical vapour deposition of or afforded brown tungsten trioxide thin films. These films were converted to yellow fully oxidised WO3 on annealing in air at 550 degrees C for 30 minutes. The yellow WO3 films demonstrate preferred orientation on the substrate and show interesting functional properties-photo induced hydrophilicity and photocatalytic activity.
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CAS 83-40-9 3-Methylsalicylic acid

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