|Description||A cardioselective M2-cholinoblocking compound semi-synthetic derivative of Imperialine alkaloid Derived from base alkaloid Imperialine, isolated from the plant Petilium eduardi and P.raddeanae (Liliaceae fam.)|
Sesquiterpene lactone , from plants of the Compositae family, an antiatherosclerotic, angioprotective, hypolipidemic and anti-inflammatory.
Irofulven is a semisynthetic sesquiterpene derivative of illudin S, a natural toxin isolated from the fungus Omphalotus illudens. Irofulven alkylates DNA and pr...
Camptothecin (CPT) is a potent DNA enzyme topoisomerase I (topo I) inhibitor with an IC50 and IC70 of 50 nM and 0.225 μM for breast cancer cell line MDA-MB-231.
an antagonist of the nicotinic acetylcholine receptor at the neuromuscular junction. Erabutoxin B from Laticauda semifasciata (Sea Snake)
Tropane alkaloid, from plants of the Convolvulus genus,
β-Bungarotoxin is a form of bungarotoxin that is fairly common in Krait (Bungaros multicinctus) venoms. A pre-synaptic toxin with enzymatic activity.
An excitatory scorpion toxin. Polypeptide, of 77 amino acids cross-linked by 4 disulfide bridges. Recombinant toxin produced in<br/>Escherichia coli initialy fr...
Na+,K+-ATPase inhibiting activity of cardiac glycosides from Erysimum cheiranthoides
A potent non-competitive GABA antagonist in mammalian, molluscan and insects; convulsant;laboratory insecticide.
Selective blocker of the big conductance Ca2+-activated K+ channel.
Psoralen is a photoactive probe that has been used to investigate nucleic acid structure and function. It intercalates into DNA and, when activated by ultraviol...
Monomethylauristatin F Hcl(MMAF Hcl) is an antitubulin agent that inhibit cell division by blocking the polymerization of tubulin; lower cytotoxic activity than...
SNX-482 has been isolated from the venom of the Spider Hysterocrates gigas (African tarantula). SNX-482 modulates the R-type current associated with the class α...
M2 muscarinic receptor antagonist; myorelaxant. Steroid alkaloid derivative of Imperialine from the plant Petilium eduardi, and P. raddeanae.
Amaryllidaceae alkaloid from plants of the Amaryllidaceae family. A hypotensive, sedative. Amaryllidaceae alkaloid , from plants of the Amaryllidaceae family.
Ionotropic GABAA receptors are ligand-gated ion channels that facilitate the passing of chloride ions across the cell membrane and promote an inhibitory influen...
Diterpenoid Alkaloid Extracted from Aconitum orientale
An analog of Veratridine; Na+ channel activator; potent neurotoxic; depolarizing agent on membranes of nerve terminal, muscle and gland cells.
α-Cobratoxin is a substance of the venom of certain Naja cobras. It is a nicotinic acetylcholine receptor (nAChR) antagonist which causes paralysis by preventin...
Diacetylkorseveriline is an antiarrhythmic (classes i and iv), belonging to a novel structural class. effective against arrhythmia caused by aconitine,CaCl2, el...