29-Hydroxyfriedelan-3-one - CAS 39903-21-4
Catalog number: 39903-21-4
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
Molecular Weight:
Chemical Family:
29-Hydroxyfriedelan-3-one isolated from the herbs of Euonymus alatus (Thunb.) Sieb.
Publictions citing BOC Sciences Products
  • >> More
> 95%
Quality Standard:
Enterprise Standard
1.Triterpenes from Tripterygium wilfordii Hook.
Yang JH;Luo SD;Wang YS;Zhao JF;Zhang HB;Li L J Asian Nat Prod Res. 2006 Jul-Aug;8(5):425-9.
Two new friedelane-type triterpenes, tripterfrielanons A (1) and B (2), along with six known triterpenoids, friedelin (3), canophyllal (4), canophyllalic acid (5), 3-oxo-29-hydroxyfriedelane (6), wilforlide A (7), wilforlide B (8), have been isolated from the EtOH extract of the roots of Tripterygiumwilfordii Hook.f. Compounds 4, 5, 6 were isolated for the first time from this plant. The new triterpenes 1 and 2 exhibited mild cytotoxic activity against human Hela cell lines in vitro. The assay showed the IC50 of 1 and 2 were 8.5 and 25 microg/mL, respectively.
2.Friedelane triterpenoids from Maytenus macrocarpa.
Chávez H;Estévez-Braun A;Ravelo AG;González AG J Nat Prod. 1998 Jan;61(1):82-5.
A set of friedelane triterpenoids has been isolated from the stem bark exudates of Maytenus macrocarpa. It includes a new friedelan triterpene (1), together with the known compounds friedelin, 3-oxo-29-hydroxyfriedelane, 3-oxofriedelan-25-al, and canophyllol. The structures of these compounds were elucidated by spectroscopic and chemical evidence. Complete 1H and 13C assignments were achieved by 2D NMR spectroscopy. The new compound showed weak activity against aldose reductase. It did not display antitumor activity against P-388 lymphoid neoplasm, A-549 human lung carcinoma, HT-29 human colon carcinoma, or MEL-28 human melanoma cell lines.
3.Triterpenes and phytosterols as human leucocyte elastase inhibitors.
Mitaine-Offer AC;Hornebeck W;Sauvain M;Zèches-Hanrot M Planta Med. 2002 Oct;68(10):930-2.
Ten triterpenes and phytosterols beta-amyrin, lupeol, lupeol acetate, ursolic acid, friedelin, canophyllol, 29-hydroxy-friedelan-3-one, beta-sitosterol, 3- O-beta- D-glucopyranosyl-beta-sitosterol, 3-O-(6'- O-palmitoyl)-beta-D-glucopyranosyl-beta-sitosterol, were evaluated as potential inhibitors of human leucocyte elastase (HLE). In this series, lupeol, ursolic acid and canophyllol showed marked HLE inhibitory activity with IC(50) values at 1.9 microM, 4.4 microM, and 2.5 microM, respectively. It appeared that HLE inhibition depended on the presence and the orientation of two reactive groups in the tested molecules, distant from 10-12 A, reacting with Arg-217 in S(4) -S(5) subsites of the extended substrate-binding domain of HLE, and S(3), respectively.
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

Related Triterpenoids Products

Rubiprasin A
(CAS: 125263-65-2)

Rubiprasin A is a natural triterpenoid compound found in several plants.

CAS 989-61-7 Limonol

(CAS: 989-61-7)

Limonol isolated from the barks of Melia azedarach L.

CAS 126005-94-5 28-Deoxonimbolide

(CAS: 126005-94-5)

28-Deoxonimbolide is a natural triterpenoid found in the barks of Azadirachta indica.

CAS 124961-61-1 Raddeanoside R8

Raddeanoside R8
(CAS: 124961-61-1)

CAS 247036-52-8 6-Deoxy-9α-hydroxycedrodorin

(CAS: 247036-52-8)

6-Deoxy-9α-hydroxycedrodorin isolated from the herbs of Cedrela odorata.

CAS 6610-55-5 Glochidone

(CAS: 6610-55-5)

Glochidone isolated from the herbs of Glochidion puberum L.

CAS 35738-25-1 3β-Acetoxy-11α,12α-epoxyoleanan-28,13β-olide

(CAS: 35738-25-1)

3beta-Acetoxy-11alpha,12alpha-epoxyoleanan-28,13beta-olide is a natural compound isolated from the branches of Eysenhardtia platycarpa.

CAS 78574-94-4 Cycloastragenol

(CAS: 78574-94-4)

CAS 381691-22-1 28-Hydroxy-3-oxoolean-12-en-29-oic acid

28-Hydroxy-3-oxoolean-12-en-29-oic acid
(CAS: 381691-22-1)

28-Hydroxy-3-oxoolean-12-en-29-oic acid is a natural triterpenoid found in the herbs of Celastrus paniculatus.

CAS 3604-92-0 Diepiserratenediol

(CAS: 3604-92-0)

Diepiserratenediol is a natural compound isolated from the whole plants of Lycopodium japonicum Thunb.

CAS 96553-02-5 gypsogenin-3-O-glucuronide

(CAS: 96553-02-5)

Methyl gypsogenin 3-O-beta-D-glucuronopyranoside can be isolated from the seeds of Momordica cochinchinensis.

CAS 147850-78-0 Filic-3-en-25-al

(CAS: 147850-78-0)

Filic-3-en-25-al is a natural compound isolated from the whole plant of Adiantum lunulatum.

CAS 103917-26-6 Lupeol caffeate

Lupeol caffeate
(CAS: 103917-26-6)

Lupeol caffeate is a natural triterpenoid found in the herbs of Celastrus orbiculatus, it exhibits the activity of anti-malarial.

CAS 156009-80-2 Vina-ginsenoside R4

Vina-ginsenoside R4
(CAS: 156009-80-2)

Vina-ginsenoside R4 is a triterpenoid vina-ginsenoside standard extracted from Panax ginseng. Panax ginseng is a familiar herbal medicine which has been used as...

CAS 91095-51-1 3,6,19,23-Tetrahydroxy-12-ursen-28-oic acid

3,6,19,23-Tetrahydroxy-12-ursen-28-oic a
(CAS: 91095-51-1)

3,6,19,23-Tetrahydroxy-12-ursen-28-oic acid is a natural triterpenoid found in the herbs of Uncaria sessilifructus.

CAS 108340-60-9 Ganoderic acid D

Ganoderic acid D
(CAS: 108340-60-9)

Ganoderic acid D (GAD) is one of the major components in Ganoderma triterpenes. GAD treatment for 48 h inhibited the proliferation of HeLa human cervical carcin...

CAS 173991-81-6 22-Hydroxy-3-oxo-12-ursen-30-oic acid

22-Hydroxy-3-oxo-12-ursen-30-oic acid
(CAS: 173991-81-6)

22-Hydroxy-3-oxo-12-ursen-30-oic acid isolated from the herbs of Euonymus alatus.

CAS 1016260-22-2 Kadsuracoccinic acid A

Kadsuracoccinic acid A
(CAS: 1016260-22-2)

Kadsuracoccinic acid A is a natural compound isolated from the herb of Kadsura coccinea.

CAS 55497-79-5 Myriceric acid B

Myriceric acid B
(CAS: 55497-79-5)

Myriceric acid B isolated from the root bark of Myrica cerifera L. It exhibits cytotoxic activity towards the MOLT-3 cell line.

Oleanolic acid - 3-O-β-D- Galactosyl( 1→

Oleanolic acid - 3-O-β-D- Galactosyl( 1→3)-β-D-glucosyl( 1→3)-α-L-rhamnosyl(1→2)-α-L-arabinoside is a lupane-type triterpenoid glycoside isolated from Pulsatill...

Chemical Structure

CAS 39903-21-4 29-Hydroxyfriedelan-3-one

Quick Inquiry

Verification code

Featured Items