|Description||20S-Protopanaxatriol (g-PPT), a dammarane-type tetracyclic terpene sapogenin, may be used to study its binding to and modulation of cell function via glucocortoid (GR) and oestrogen (ER) receptors.|
A 357300 hydrochloride
A 357300 hydrochloride is a potent and reversible inhibitor of methionine aminopeptidase-2 (MetAP-2). In murine models, it significantly inhibits CHP-134-derive...
7-Deaza-2’-C-methyladenosine is a hepatitis C virus (HCV) polymerase inhibitor.
PMX 464, a thiol-reactive quinol and putative thioredoxin inhibitor, is a putative inhibitor of the thioredoxin-thioredoxin reductase (Trx-TrxR) system, which s...
Gue 1654 is an oxoeicosanoid receptor 1 (OXE-R) modulator selectively inhibiting Gβγ but not Gαi signaling upon activation of the Gαi-βγ heterotrimer by OXE-R. ...
WKYMVM is a selective agonist for the formyl peptide receptors FPR2 and FPR3 that is expressed on immune cells. WKYMVM induces calcium mobilization in FPR2-HL-6...
AD80, also called as A-196, is a multikinase inhibitor that inhibits against human BRAF, S6K, and SRC and shows strong activity against RET inhibitor.
CC-17368, a hydroxyisoindole derivative, is a metabolites of pomalidomide and has potential activity in anticancer study like multiple myeloma.
MMK 1 is a potent and selective human formyl peptide receptor FPR2 agonist (EC50 = 1, 2 and > 10 000 nM at mFRP2, hFPR2 and hFPR1 respectively). Some findings s...
Benazepril is a drug of the angiotensin-converting enzyme (ACE) inhibitor used to treat high blood pressure.
Curdione, a sesquiterpene compound, could probably be a candidate for inflammatory study and cancer chemopreventive agents.
FCE 26644, also known as PNU-145156E, has been found to be a angiogenesis inhibitor that could have probable effect against solid tumours. It has already been d...
PFK15 is a potent and selective 6-phosphofructo-2-kinase (PFKFB3) with IC50 of 207 nM.
Foresaconitine is a norditerpenoid alkaloid isolated from the processed tubers of Aconitum carmichaeli.
Docosatrienoic acid is a rare ω-3 fatty acid, not readily detected in normal phospholipid PUFA pools. Docosatrienoic acid inhibits LTB4 binding to pig neutrophi...
XEN445 is a potent and selective endothelial lipase inhibitor with IC50 of 0.237 μM.
ZIP (Scrambled) is a scrambled control peptide for ZIP.
KAT681 is a novel liver-selective thyromimetic displaying strong hypolipidemic properties without cardio-toxic effects.
Micheliolide could effectively attenuate the high glucose-stimulated activation of NF-κB, the degradation of IκBα, and the expression of MCP-1, TGF-β1 and FN in...
DPO-1, a blocker of IKur ultrarapid delayed rectifier potassium current and KV1.5 channels, has been found to exhibit activities in preventing atrial arrhythmia...
MDL-72274 is a selective SSAO inhibitor. It is a potent (IC50 = 10(-9) M) inhibitor of both MAO-B and SSAO, with 190-fold lower affinity for MAO-A. MDL-72974 ca...