2019-9 monthly featured products have been updated. BOC Sciences is a leading chemical supplier providing superior and high-purity featured products, which are ready to be ordered from stock.
This batch of featured products consists of 171 products, containing inhibitors (agonists and antagonists), APIs, intermediates and impurities, bioactive natural compounds, metabolites, carbohydrate, nucleotide, pharmaceutical excipients, fluorescent dye, ADCs cytotoxin and linker, as well as building blocks.
Inhibitors (agonists and antagonists) and APIs are the most recommended products in this batch. We provide multiple types of APIs as NSAIDs Ibuprofen piconol (B0046-448719) and Nepafenac (B0046-464115), antibiotics Voriconazole (B0046-463837), Solithromycin (B0046-465272), Metalaxyl (B0046-094869), Doripenem hydrate (B0046-463932), insecticide Thiacloprid (B0046-054627), pesticide/herbicide Cyflumetofen (B0046-141479), Prothioconazole (B0046-223338), Metribuzin (B0046-057609), Metolachlor (B0046-093373), and some antihistamine, antitumor, antiemetic, anticoagulant agent as well as ion chelator, anesthetic, coccidiostat, muscle relaxant included. In addition to APIs described above, some novel small-molecule inhibitors developed for death-threatening disease treatment are also worth noting. ML390 (B0084-008137), a human dihydroorotate dehydrogenase (DHODH) inhibitor, has been shown to induce differentiation in acute myeloid leukemia (AML) cell lines. DHODH is a key enzyme catalyzing the oxidation of dihydroorotate to orotate in de novo pyrimidine biosynthesis pathway, which is associated with mitochondrial bioenergetics, cell proliferation, ROS production, and apoptosis in certain cell types. With DHODH established as a target for AML and other refractory disease therapy, more inhibitors are currently under evaluation and development.
Various API impurities are offered in this batch. Rivaroxaban (B0084-067210), under the brand name Xarelto, is a prescription blood thinner indicated for the prevention and treatment of deep vein thrombosis (DVT), pulmonary embolism (PE) and major cardiovascular events. Several rivaroxaban impurities, 4-(2,4-Diaminophenyl)morpholin-3-one (B0145-008028), Rivaroxaban Impurity A hydrochloride (B0145-008069), Rivaroxaban Pseudodimer (B0145-008646), and Rivaroxaban Amine Impurity (B0145-008649) have been available in BOC Sciences. Some other impurities as diphenhydramine impurity Diphenhydramine Impurity C hydrochloride (B0776-470246), pioglitazone impurity Pioglitazone EP Impurity B (B0198-387033), paclitaxel impurity 10-Desacetyl Paclitaxel (B1473-478487), prednisolone impurity 6-alpha-methyl prednisolone aceponate (B1742-078560), are also ready for customers’ order.