|Description||2-MPPA is a selective glutamate carboxypeptidase II (GCP II) inhibitor (IC50 = 90 nM), which is selective for GCP II over NMDA, kainate and AMPA glutamate receptors and MMP-1, -2, -3, -7, -9, ACE and NEP metalloproteases. 2-MPPA can be used in the treatment of neurological disorders associated with excessive activation of glutamatergic systems. Attenuates glutamate transmission resulting in the relief of neuropathic pain. This compound has neuroprotective properties.|
|Solubility||Water to 100 mM; DMSO to 100 mM|
|Storage||Store in a cool and dry place (or refer to the Certificate of Analysis).|
CPA inhibitor is a potent inhibitor for carboxypeptidase A (CPA).
Carboxypeptidase G2 (CPG2) Inhibitor
A novel Carboxypeptidase G2 (CPG2) Inhibitor, Antitumor agents.
2-MPPA is a selective glutamate carboxypeptidase II (GCP II) inhibitor (IC50 = 90 nM), which is selective for GCP II over NMDA, kainate and AMPA glutamate recep...
2-PMPA is highly potent and selective inhibitor of glutamate carboxypeptidase 2 (Ki= 275 pM) and the neuropeptidase N-acetylated α-linked acidic dipeptidase (NA...