|Description||2-APB, a transient receptor potential (TRP) activator for TRPV1, TRPV2, and TRPV3, could probably be used against diseases caused by hypersensitivity and temperature misregulation.|
|Purity||≥98% by HPLC|
L-R is a vanilloid TRPV1 (VR1) receptor antagonist peptide (IC50 ~ 0.1 μM).
M 084 hydrochloride is a TRPC4/5 channel blocker with IC50 values of 3.7-10.3 and 8.2 μM, respectively. It weakly blocks TRPC3 channels. It has rapid anxiolytic...
RQ-00203078 is a potent, selective and orally active TRPM8 antagonist (IC50 values are 5.3 and 8.3 nM for rat and human channels respectively). RQ-00203078 bloc...
TRPV antagonist 1
TRPV antagonist 1 is a transient receptor potential vanilloid (TRPV) antagonist (IC50= < 250 nM).
AM 0902 is an effective and selective TRPA1 antagonist and has been found to exhibit activities in biological pathways associated with pain.
PPAHV is a non-pungent vanilloid TRPV1 (VR1) receptor agonist (Ki = 3.1 μM), and is agonist at rat VR1(TRPV1) (EC50 between 3 and 10 μM) but virtually inactive ...
CIM 0216 has been found to be a selective TRPM3 agonist and could stimulate the release of insulin from pancreatic islet cells.
MRS 1477, a dihydropyridine derivative, is a TRPV1 positive allosteric modulator, and potentiates vanilloid and proton activation of TRPV1 channels.