2-Aminoheptane - CAS 123-82-0
Catalog number:
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
Molecular Weight:
2-Aminoheptane, a fatty Amine compound, is commonly used in proteomics research and could also be used to product some A3 adenosine receptor antagonists.
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Colorless liquid
Flammables area
2-Aminoheptane is commonly used in proteomics research and could also be used to product some A3 adenosine receptor antagonists.
Shelf Life:
As supplied, 2 years from the QC date provided on the Certificate of Analysis, when stored properly
Boiling Point:
Canonical SMILES:
1.Resolution of enantiomeric amides on a Pirkle-type chiral stationary phase. A comparison of subcritical fluid and liquid chromatographic approaches.
Macaudiere P, Tambute A, Caude M, Rosset R, Alembik MA, Wainer IW. J Chromatogr. 1986 Dec 26;371:177-93.
Subcritical and supercritical fluid chromatography (SubFC and SFC) have been evaluated for the resolution of an homologous series of enantiomeric amides. The solutes were the 2-naphthoyl amides of an homologous series of amines, ranging from 2-aminobutane to 2-aminoctane, and the p-methyl-, p-methoxy- and p-chlorophenylamides of 2-aminoheptane. The chiral stationary phase (CSP) used was the covalent form of (R)-N-(3,5-dinitrobenzoyl)phenylglycine. In liquid chromatography (LC) the mobile phase comprised hexane-2-propanol--acetonitrile (97:3:0.5) at a flow-rate of 2 ml/min and temperatures of 20-35 degrees C. In SFC, the mobile were various mixtures of carbon dioxide and polar modifiers, such as alcohols, chloroform and water. For the best conditions in LC, the chiral resolution, alpha, increased through the homologous series from alpha = 1.03 for the amide derived from 2-aminobutane to alpha = 1.11 for the 2-aminooctane amide. The values of alpha observed for the pi-basic amides of 2-aminoheptane (p-methyl and p-methoxy) were greater than that observed for the pi-acidic amide (p-chloro), i.
2.Biogenic amine-ionophore interactions: Structure and dynamics of lasalocid (X537A) complexes with phenethylamines and catecholamines in nonpolar solution.
Shen C1, Patel DJ. Proc Natl Acad Sci U S A. 1977 Nov;74(11):4734-8.
The ionophore lasalocid A forms 1:1 complexes with phenethylamines (1-amino-1-phenylethane and 1-amino-2-phenylethane) and catecholamines (dopamine and norepinephrine) in nonpolar solution. We have undertaken high-resolution proton nuclear magnetic resonance studies to deduce structural and kinetic information on the ionophore-biogenic amine complexes in chloroform solution. The coupling constant, chemical shift, and relaxation time data demonstrate that the lasalocid backbone conformation and the primary amine binding sites in the complexes are similar to those determined earlier for the alkali and alkaline earth complexes of this ionophore in solution. The exchange of lasalocid between the free acid (HX) and the primary amine complexes (RNH(3)X) in chloroform solution have been evaluated from the temperature-dependent line shapes at superconducting fields. The kinetic parameters associated with the unimolecular dissociation [Formula: see text] and the bimolecular exchange [Formula: see text] reactions have been deduced from an analysis of the lifetime of the complex as a function of the reactant concentrations.
3.Screening and confirmation capabilities of liquid chromatography-time-of-flight mass spectrometry for the determination of 200 multiclass sport drugs in urine.
Domínguez-Romero JC1, García-Reyes JF1, Lara-Ortega FJ1, Molina-Díaz A2. Talanta. 2015 Mar;134:74-88. doi: 10.1016/j.talanta.2014.10.050. Epub 2014 Oct 31.
In this article, a screening method for the determination of 200 sport drugs in human urine has been developed using liquid-chromatography electrospray time-of-flight mass spectrometry (LC-TOFMS). The chromatographic separation of the targeted doping agents was carried out by fast liquid chromatography using a C18 column (4.6×50 mm) with 1.8 μm particle size. Accurate mass measurements of the selected ion (typically [M+H](+) and [M-H](-)) along with retention time matching was used for the screening and detection of the targeted species. The proposed methodology comprised also a simple sample treatment stage based on solid-phase extraction (SPE) with polymeric cartridges. The SPE method displayed satisfactory recoveries rates (between 70 and 120%) for the majority of the compounds at both concentration levels tested (2.5 and 25 μg L(-1)). The overall performance of the method was satisfactory with all 200 compounds fulfilling WADA minimum required performance levels (MRPLs), with limits of quantitation lower than 1 μg L(-1) for 80% of the compounds, and showing an appropriate linearity (r(2)>0.
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CAS 123-82-0 2-Aminoheptane

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