|Description||2(acute)-Deoxyguanosine is composed of the purine nucleoside guanine linked by its N9 nitrogen to the C1 carbon of deoxyribose. It is a purine nucleoside that upon sequential phosphoylation (kinases) forms dGTP which is used by DNA polymerases and reverse transcriptases to synthesis DNA(s). It is the most electron rich of the four canonical bases and includes many nucleophilic sites which are susceptible to oxidative damage. It is useful reagents to study mechanisms of oxidative damage to nucleosides and nucleotides.|
|Synonyms||Deoxyguanosine; Guanine deoxyriboside|
This active molecular is a selective Porcupine protein inhibitor and IC50 value is 0.8nM. GNF-6231 shows efficient pathway inhibition and induced robust antitum...
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5(acute)-GTP trisodium salt
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Activator of pyruvate kinase isoenzyme M2 (PKM2), an enzyme involved in glycolysis. Since all tumor cells exclusively express the embryonic M2 isoform of PK, it...
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