|Description||This molecular is a [18F] PET (positron emission tomography) radiotracer. It can accumulate in cells presenting apoptosis-specific membrane alterations. ML-10 allows for the detection of apoptotic cells located in atherosclerotic plaques. In Jun 2015, GlaxoSmithKline terminated a phase II trial in Solid tumours (Diagnosis) in United Kingdom. In Mar 2016, Phase-II for solid tumours, lung cancer and head Brain metastases and neck cancer (Diagnosis) in USA was suspended|
|Synonyms||ML 10;[18F]-ML-10; ApoSense-PET; F-18-ML-10;|
|Solubility||Soluble in DMSO|
|Application||used as an Cancer Diagnostic reagents|
|Quality Standard||In-house standard|
|Shelf Life||2 month in rt, long time|
|Current Developer||Aposense; GlaxoSmithKline|
A skeletal muscle relaxant used to treat drug-induced parkinsonism and to relieve pain from muscle spasm.
Org 25543 hydrochloride
Org 25543 hydrochloride is a glycine transporter type 2 inhibitor with IC50 value of 16 nM.
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CB 3988 is a bio-active chemical compound.